高级别卵巢上皮肿瘤和术中冷冻切片:诊断不一致的后果

IF 0.1 Q4 PATHOLOGY
C. Felicelli, Luis Z. Blanco
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引用次数: 0

摘要

卵巢肿瘤是术中常见的标本(冷冻切片),因为准确的诊断对于确定手术的下一步是必要的。我们提出的情况下,79岁的妇女5.3厘米的右卵巢病变,以及一个大的阑尾肿块。卵巢病变的冰冻切片显示高级别肿瘤伴腔内坏死。这些形态学发现,加上结肠肿块的存在,导致术中会诊诊断为“高级别腺癌,倾向于胃肠道原发转移”,并在切除阑尾和盲肠后结束手术。然而,永久性切片显示高级别浆液性癌。我们回顾了卵巢冷冻切片高度病变的鉴别诊断,检查可能发生的挑战,并讨论了潜在的下游影响和患者护理的后果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
High-Grade Ovarian Epithelial Tumor and Intraoperative Frozen Section: Consequences of a Discordant Diagnosis
Abstract Ovarian neoplasms are a common specimen received for intraoperative consultation (frozen section) as an accurate diagnosis is necessary to determine the next steps in surgery. We present the case of a 79-year-old woman with a 5.3-cm right ovarian lesion as well as a large appendiceal mass. The frozen section of the ovarian lesion showed a high-grade tumor with areas of luminal necrosis. These morphologic findings, along with the presence of a colonic mass, led to an intraoperative consultation diagnosis of “high grade adenocarcinoma, favor metastasis from gastrointestinal tract primary,” and to the surgery ending after removal of the appendix and cecum. However, the permanent section revealed high-grade serous carcinoma. We review the differential diagnosis of high-grade ovarian lesions on frozen section, examine the challenges that can occur, and discuss the potential downstream effects and consequences for patient care.
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CiteScore
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