颈鞭综合征患者的中枢疼痛敏化:综述

Diego Serrano-Muñoz , Julio Gómez-Soriano , Gerardo Ávila-Martín , Iriana Galán-Arriero , Luis María Romero-Muñoz , Julian S. Taylor , Andrés Barriga-Martín
{"title":"颈鞭综合征患者的中枢疼痛敏化:综述","authors":"Diego Serrano-Muñoz ,&nbsp;Julio Gómez-Soriano ,&nbsp;Gerardo Ávila-Martín ,&nbsp;Iriana Galán-Arriero ,&nbsp;Luis María Romero-Muñoz ,&nbsp;Julian S. Taylor ,&nbsp;Andrés Barriga-Martín","doi":"10.1016/j.rslaot.2017.02.001","DOIUrl":null,"url":null,"abstract":"<div><p>The cervical whiplash syndrome is a disorder that affects a many people following road traffic accidents and which has a high economic cost. The disorders associated with whiplash syndrome are numerous, and include neck pain and muscle stiffness, headache, and dizziness. In approximately 50% of people who suffer from whiplash, the initial pain develops and is maintained into the chronic phase. Mechanisms of central sensitization to pain has been recognized as an important pathophysiological mechanism which may mediate various types of pain and which may be responsible for its chronification in these patients, as they show signs of hypersensitivity to pain, including decreased pain pressure thresholds and altered temporal summation to noxious stimuli. With regards to treatment, although there is a wide range of physical therapies available to treat whiplash disorders, currently there is no consensus on which therapy is most effective. Understanding the mechanisms by which pain becomes chronic following whiplash will help to develop an effective therapy that could directly treat the disorders associated with this pathology in many people with chronic pain symptomatology based on the evidence-based diagnosis of pathophysiological mechanisms.</p></div>","PeriodicalId":101114,"journal":{"name":"Revista Latinoamericana de Cirugía Ortopédica","volume":"1 3","pages":"Pages 102-107"},"PeriodicalIF":0.0000,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rslaot.2017.02.001","citationCount":"4","resultStr":"{\"title\":\"Sensibilización central al dolor en pacientes con síndrome del latigazo cervical: una revisión\",\"authors\":\"Diego Serrano-Muñoz ,&nbsp;Julio Gómez-Soriano ,&nbsp;Gerardo Ávila-Martín ,&nbsp;Iriana Galán-Arriero ,&nbsp;Luis María Romero-Muñoz ,&nbsp;Julian S. Taylor ,&nbsp;Andrés Barriga-Martín\",\"doi\":\"10.1016/j.rslaot.2017.02.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The cervical whiplash syndrome is a disorder that affects a many people following road traffic accidents and which has a high economic cost. The disorders associated with whiplash syndrome are numerous, and include neck pain and muscle stiffness, headache, and dizziness. In approximately 50% of people who suffer from whiplash, the initial pain develops and is maintained into the chronic phase. Mechanisms of central sensitization to pain has been recognized as an important pathophysiological mechanism which may mediate various types of pain and which may be responsible for its chronification in these patients, as they show signs of hypersensitivity to pain, including decreased pain pressure thresholds and altered temporal summation to noxious stimuli. With regards to treatment, although there is a wide range of physical therapies available to treat whiplash disorders, currently there is no consensus on which therapy is most effective. Understanding the mechanisms by which pain becomes chronic following whiplash will help to develop an effective therapy that could directly treat the disorders associated with this pathology in many people with chronic pain symptomatology based on the evidence-based diagnosis of pathophysiological mechanisms.</p></div>\",\"PeriodicalId\":101114,\"journal\":{\"name\":\"Revista Latinoamericana de Cirugía Ortopédica\",\"volume\":\"1 3\",\"pages\":\"Pages 102-107\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.rslaot.2017.02.001\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Latinoamericana de Cirugía Ortopédica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2444972517300025\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Latinoamericana de Cirugía Ortopédica","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2444972517300025","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4

摘要

颈椎鞭打综合征是一种影响许多人在道路交通事故后的疾病,具有很高的经济成本。与鞭打综合征相关的疾病有很多,包括颈部疼痛和肌肉僵硬、头痛和头晕。在大约50%的遭受鞭打的人,最初的疼痛发展并维持到慢性阶段。中枢对疼痛的敏感化机制已被认为是一种重要的病理生理机制,它可能介导各种类型的疼痛,并可能导致这些患者的慢性化,因为他们表现出对疼痛超敏感的迹象,包括疼痛压力阈值降低和对有害刺激的时间累积改变。在治疗方面,虽然有多种物理疗法可用于治疗鞭扭伤,但目前对于哪种疗法最有效尚无共识。了解鞭打后疼痛变为慢性的机制将有助于开发一种有效的治疗方法,可以直接治疗许多基于循证病理生理机制诊断的慢性疼痛症状患者与该病理相关的疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sensibilización central al dolor en pacientes con síndrome del latigazo cervical: una revisión

The cervical whiplash syndrome is a disorder that affects a many people following road traffic accidents and which has a high economic cost. The disorders associated with whiplash syndrome are numerous, and include neck pain and muscle stiffness, headache, and dizziness. In approximately 50% of people who suffer from whiplash, the initial pain develops and is maintained into the chronic phase. Mechanisms of central sensitization to pain has been recognized as an important pathophysiological mechanism which may mediate various types of pain and which may be responsible for its chronification in these patients, as they show signs of hypersensitivity to pain, including decreased pain pressure thresholds and altered temporal summation to noxious stimuli. With regards to treatment, although there is a wide range of physical therapies available to treat whiplash disorders, currently there is no consensus on which therapy is most effective. Understanding the mechanisms by which pain becomes chronic following whiplash will help to develop an effective therapy that could directly treat the disorders associated with this pathology in many people with chronic pain symptomatology based on the evidence-based diagnosis of pathophysiological mechanisms.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信