埃塞俄比亚Tepi综合医院接受抗逆转录病毒治疗前护理的成年人的消耗时间和相关因素

IF 0.1 Q4 HEALTH CARE SCIENCES & SERVICES
T. Adewo, H. Asefa, H. Gesesew
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引用次数: 2

摘要

在埃塞俄比亚,抗逆转录病毒前治疗(Pre-ART)患者耗损日益受到关注。然而,很少有资料评估其规模及其相关因素。本研究评估了在埃塞俄比亚西南部Tepi总医院接受ART前治疗的成年人的消耗时间和相关因素。回顾2010年10月至2013年9月在Tepi综合医院登记的成人art前患者的记录,以寻找与时间消耗相关的因素。我们将消耗时间定义为患者参加art前服务直至消耗的时间。我们使用Kaplan Meir曲线估计生存时间,并使用log-rank检验比较不同类别患者的消耗时间。我们使用Cox风险模型来评估与磨耗时间相关的因素。我们对652名art前患者进行了337.6人年的随访,从开始到art前的结果。其中,179例患者失去随访,37例患者死亡,总体损失率为33.13%。在最初的六个月里,流失率为89.8%。未开始复方新诺明预防(AHR=1.51, 95%CI, 1.02-2.25)、合并感染结核病(TB) (AHR=2.16, 95%CI, 1.35-3.45)、居住距离医院超过10公里(AHR=1.44, 95%CI, 1.07-2.0)和未披露HIV状况(AHR=3.04)是与消耗时间显著相关的因素。未使用复方新诺明预防、结核/艾滋病毒合并感染、居住在距离卫生保健机构10公里以上以及未披露艾滋病毒状况的客户中,抗逆转录病毒治疗前患者的损耗率很高。建议在随访的前几个月对客户进行密切的随访。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Time to Attrition and Factors Associated among Adults enrolled in Pre-Anti- Retroviral Therapy Care in Tepi General Hospital, Ethiopia
Pre-antiretroviral therapy (Pre-ART) patient attrition is a growing concern in Ethiopia. Nevertheless, there is little information that assesses the magnitude and its related factors. This study assessed time to attrition and factors associated among adults enrolled in pre ART care at Tepi General Hospital in South West Ethiopia. Records of adult pre-ART patients enrolled at Tepi General Hospital from October 2010 to September 2013 were reviewed to find factors linked with time to attrition. We defined time to attrition as the period a patient was enrolled in pre-ART service till attrition. We Used Kaplan Meir curve to estimate survival time, and log-rank test to compare the time to attrition among different categories of patients. We used Cox hazard model to assess factors related with time to attrition. We followed 652 pre-ART patients for 337.6 person years of follow-up from start up to pre-ART outcomes. Of these, 179 patients were lost to follow up and 37 patients died, contributing to an overall attrition of 33.13%. During the early six months the attrition rate was 89.8%. Not starting cotrimoxazole prophylaxis (AHR=1.51, 95% CI, 1.02-2.25), being co-infected with tuberculosis (TB) (AHR=2.16, 95%CI, 1.35-3.45), living further than 10 km away from the hospital (AHR=1.44, 95%CI, 1.07-2.0), and not disclosed status of HIV(AHR=3.04) were factors significantly associated with time to attrition. Pre-ART patient attrition rate was high among clients not using cotrimoxazole prophylaxis, TB/HIV co-infected, living > 10 km from a health care facility and with undisclosed HIV status. Close follow-up of clients during the early months' follow-up period is greatly recommended.
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