Tiago Cúrdia Gonçalves, Tiago Lima Capela, José Cotter
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引用次数: 0
摘要
急性胰腺炎 (AP)、慢性胰腺炎 (CP) 和胰腺癌 (PC) 等常见胰腺疾病可能会极大地影响胰腺的正常生理功能并导致营养不良,而在这些疾病发生时采取适当的营养方法则会极大地影响患者的预后。对于 AP 患者,营养护理的目标是预防营养不良、纠正负氮平衡、减轻炎症反应以及改善局部和全身并发症及死亡率等预后。营养不良在 CP 患者中很常见,但往往是疾病的晚期表现,会导致功能能力和生活质量下降,并增加发生严重骨病、术后并发症、住院和死亡的风险。癌症相关营养不良在 PC 患者中很常见,现在人们普遍认识到,早期营养支持不仅能提高患者对疾病治疗的耐受性和反应,还能改善患者的生活质量并减少术后并发症,从而对患者的生存产生有利影响。本综述旨在强调营养的作用,并提出针对 AP、CP 和 PC 患者的系统营养方法。
Nutrition in Pancreatic Diseases: A Roadmap for the Gastroenterologist.
While common pancreatic diseases, such as acute pancreatitis (AP), chronic pancreatitis (CP), and pancreatic cancer (PC), may greatly impact the normal pancreatic physiology and contribute to malnutrition, the adequate nutritional approach when those conditions are present significantly influences patients' prognosis. In patients with AP, the goals of nutritional care are to prevent malnutrition, correct a negative nitrogen balance, reduce inflammation, and improve outcomes such as local and systemic complications and mortality. Malnutrition in patients with CP is common but often a late manifestation of the disease, leading to decreased functional capacity and quality of life and increased risk of developing significant osteopathy, postoperative complications, hospitalization, and mortality. Cancer-related malnutrition is common in patients with PC, and it is now well recognized that early nutritional support can favorably impact survival, not only by increasing tolerance and response to disease treatments but also by improving quality of life and decreasing postoperative complications. The aim of this review was to emphasize the role of nutrition and to propose a systematic nutritional approach in patients with AP, CP, and PC.
期刊介绍:
The ''GE Portuguese Journal of Gastroenterology'' (formerly Jornal Português de Gastrenterologia), founded in 1994, is the official publication of Sociedade Portuguesa de Gastrenterologia (Portuguese Society of Gastroenterology), Sociedade Portuguesa de Endoscopia Digestiva (Portuguese Society of Digestive Endoscopy) and Associação Portuguesa para o Estudo do Fígado (Portuguese Association for the Study of the Liver). The journal publishes clinical and basic research articles on Gastroenterology, Digestive Endoscopy, Hepatology and related topics. Review articles, clinical case studies, images, letters to the editor and other articles such as recommendations or papers on gastroenterology clinical practice are also considered. Only articles written in English are accepted.