吸烟者的社会人口统计和住房因素会影响和影响戒烟治疗的选择吗?

S. Leone, R. Carrozzino, Monica Tassistro, L. Robbiano, M. L. Zuccoli, Francesca Romani, A. Martelli, F. Mattioli
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引用次数: 3

摘要

已发表的数据表明,与最低限度的干预或常规护理相比,结合药物治疗和行为支持的干预措施可提高戒烟成功率;然而,标准化的行为心理治疗方案尚未得到评估。我们的主要目的是评估参加意大利戒烟中心的吸烟者的社会人口统计学和住房特征是否会影响伐尼克兰治疗和仅心理支持之间的选择。我们的次要目的是:i)根据吸烟者是否服用伐尼克兰或仅接受心理支持,通过比较呼出空气中的一氧化碳浓度来评估6个月的戒烟率(ARs);ii)评估伐尼克兰组最常报告的药物不良反应(adr),主要集中在精神事件;iii)评估男性和女性在特定伐尼克林相关不良反应方面的差异方法:纳入142名吸烟者;他们都接受了同样的心理支助方案。一组临床专家对他们进行了评估,建议他们选择其中一种戒烟方法;然后吸烟者为自己选择瓦伦尼克兰加心理治疗(VAR: 78例)或单独心理治疗(PSY: 64例)的治疗方案。结果:患者的社会人口学和心理特征对治疗选择有显著影响;使用伐尼克兰与心理治疗组的6个月ar分别为35.9%和10.9% (p<0.01);57.7%的患者报告了至少一次不良事件。结论:分析患者的社会人口学因素和心理特征,为他们提供最有效的治疗,以达到良好的戒断率是必要的。因此,本研究证实了伐尼克兰的有效性和安全性数据。我们的筛选方法和排除标准似乎是有效的辅助手段,以达到良好的治疗效果,并降低发生严重精神事件的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Could Smokers Socio-Demographic and Housing Factors Affect and Influence the Choice Between Smoking Cessation Therapies?
Introduction: The published data suggest that interventions which combine pharmacotherapy and behavioural support increase success rates of smoking cessation compared to minimal intervention or usual care; however, a standardized behavioural psychotherapy programme has not been assessed yet. Our main aim was to assess if socio-demographic and housing characteristics of smokers attending an Italian smoking cessation centre, could have influenced the choice between varenicline therapy and psychological support only. Our secondary aims were: i) to evaluate the 6-month abstinence rates (ARs), confirmed by comparing exhaled air carbon monoxide concentrations, in smokers according to whether they took varenicline or received only psychological support; ii) to assess the most frequently reported adverse drug reactions (ADRs) by the varenicline group, mainly focusing on psychiatric events; iii) to evaluate the differences between men and women with regard to specific varenicline-related ADRs Method: 142 smokers were enrolled; all of them received the same psychological support programme. They were evaluated by a team of clinical experts, who advised them to opt for either one quitting method or the other; then the smokers chose themselves a treatment option of either varenicline plus psychotherapy (VAR: 78 patients) or psychotherapy alone (PSY: 64 patients). Results: Socio-demographic and psychological characteristics of patients have significantly influenced the treatment choice; the 6-month ARs were 35.9% versus 10.9% (p<0.01) in those using varenicline versus psychotherapy, respectively; 57.7% of the patients reported at least one adverse event. Conclusion: The analysis of socio-demographic factors and psychological characteristics of patients seems to be necessary to offer them the most effective therapy in order to achieve good abstinence rates. Therefore, this study confirms the data about the efficacy and safety of varenicline. Our screening methods and exclusion criteria seem to be valid aids to achieving good therapeutic outcomes with a low risk of occurrence of severe psychiatric events.
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