有机溶剂萃取氨咪唑及其代谢物

Q4 Chemistry

Proceedings of the National Academy of Sciences of Belarus, Chemical Series Pub Date : 2023-06-05 DOI:10.29235/1561-8331-2023-59-2-139-149

A. G. Polonevich, S. M. Leschev, V. A. Bulhakava, L. Belysheva

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引用次数: 0

摘要

测定了咪唑及其3种主要代谢物(DMFF、DMF、DMA)在水-有机溶剂(正己烷、甲苯、二氯甲烷、氯仿)萃取体系中的分布常数。通过对各体系物质分布的分析，确定了二氯甲烷为同时测定蜂蜜中阿米特拉兹及其代谢物液-液萃取方法的最佳选择。不同添加剂在水-乙腈溶液中的稳定性研究表明，在水-乙腈混合物(1:1,vol.)中，50mm氨水溶液可作为样品最终溶液的溶剂。

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Extraction of amitraz and its metabolites with organic solvents

The distribution constants of amitraz and its three main metabolites (DMFF, DMF, DMA) for water–organic solvent (n-hexane, toluene, dichloromethane, chloroform) extraction systems were estimated. Based on the analysis of the substances distribution in the studied systems, it was established that dichloromethane is the optimal choice for amitraz and its metabolites liquid-liquid extraction for method development for their simultaneous determination in honey. Amitraz stability study in water-acetonitrile solutions with various additives demonstrated that 50 mM ammonia solution in water– acetonitrile mixture (1 : 1, vol.) should be used as solvent for the samples final solutions.

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来源期刊

Proceedings of the National Academy of Sciences of Belarus, Chemical Series Chemistry-Chemistry (miscellaneous)

CiteScore

0.30

自引率

0.00%

发文量