一种新型便携式生命支持呼吸机与有创通气家庭用户的初步临床评价

J. Yarascavitch, C. Vogler, S. Cannon-Bailey
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引用次数: 0

摘要

背景:Trilogy Evo (Philips呼吸器,Murrysville PA)是一种新型生命支持呼吸机,为成人和儿童患者提供有创和无创通气,最低体重为2.5kg。目的:将Trilogy Evo呼吸机的性能与用户现有呼吸机的参数进行比较。方法:纳入经气管造口管有创机械通气患者(IPAP 15.9±3.2cmH2O, EPAP 5.3±1.6cmH2O,潮气量263±166ml)。在基线时,用户在其当前呼吸机(LTV或Trilogy)上监测15分钟,然后在Trilogy Evo上设置至少15分钟,并使用以下一种或多种电路:被动,ActivePAP, Active Flow和双肢。记录脉搏血氧(SpO2)和末潮CO2 (EtCO2)。结果:13名参与者(7名男性,年龄11.3±10.1岁)完成了研究。采用的模式有SIMV-VC (n=9)、S/T (n=3)和A/C-PC (n=1)。Trilogy Evo被动回路设置为IPAP 15.4±3.7 cmH2O, EPAP 5.2±1.5 cmH2O,潮气量236±166 ml。EtCO2 mmHg(基线31.6±6.3 vs Trilogy Evo 29.7±6.9)或SpO2%(基线97.3±1.8 vs Trilogy Evo 97.6±1.2)无临床差异。对于气管周围有明显泄漏的用户,由于Trilogy Evo上的无源电路的泄漏补偿算法,需要降低潮气量和/或压力设置,以匹配基线治疗。结论:在本组患者中,根据SpO2和EtCO2值,Trilogy Evo提供了有效的通气。泄漏补偿功能可能为气道泄漏问题的患者提供益处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A preliminary clinical evaluation of a new portable life support ventilator with invasively ventilated home users
Background: Trilogy Evo (Philips Respironics, Murrysville PA) is a new life support ventilator that provides invasive and non-invasive ventilation to adult and pediatric patients with a minimum weight of 2.5kg. Aims: To evaluate the performance of the Trilogy Evo ventilator compared to parameters from user’s current ventilator. Methods: Patients treated with invasive mechanical ventilation via tracheostomy tube (IPAP 15.9 ± 3.2cmH2O, EPAP 5.3 ± 1.6cmH2O, and tidal volume 263 ± 166ml) were enrolled. At baseline, users were monitored on their current ventilator (LTV or Trilogy) for 15 minutes then were set-up on the Trilogy Evo for at least 15 minutes with one or more of the following circuits: Passive, ActivePAP, Active Flow and Dual Limb. Pulse oximetry (SpO2) and End Tidal CO2 (EtCO2) were recorded. Results: Thirteen participants (7 males, age 11.3 ± 10.1) completed the study. Modes utilized were SIMV-VC (n=9), S/T (n=3), and A/C-PC (n=1). Trilogy Evo passive circuit settings were IPAP 15.4 ± 3.7 cmH2O, EPAP 5.2 ± 1.5 cmH2O, and tidal volume 236 ± 166 ml. No clinical difference in EtCO2 mmHg (baseline 31.6 ± 6.3 vs Trilogy Evo 29.7 ± 6.9) or SpO2% (baseline 97.3 ± 1.8 vs Trilogy Evo 97.6 ± 1.2) were detected. In users with significant leaks around their trach tubes, the tidal volume and/or pressure settings needed to be decreased to match baseline therapy due to leak compensation algorithms with the passive circuit on Trilogy Evo. Conclusion: In this group of patients, Trilogy Evo provided effective ventilation based on SpO2 and EtCO2 values. The leak compensation capabilities may offer benefits to patients with airway leak issues.
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