柠檬酸衍生可生物降解弹性体的研究进展

R. T. Tran, Yi Zhang, Dipendra Gyawali, Jian Yang
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引用次数: 59

摘要

生物可降解弹性体近年来被广泛应用于生物医学工程的许多领域,如组织工程、药物输送和生物成像。特别是,最近的研究进展导致了柠檬酸基聚合物的产生,这些聚合物具有增强的机械性能、新颖的交联设计策略、纳米多孔特征和独特的光致发光能力。本综述将涵盖生物医学工程领域中涉及柠檬酸衍生的可生物降解生物材料的最新专利,包括聚(二醇柠檬酸酯)及其复合材料、交联聚氨酯掺杂聚酯(CUPEs)、聚(马来酸亚烯柠檬酸酯)(PAMCs)、聚(木糖醇共柠檬酸酯)(PXC)和脂肪族可生物降解光致发光聚合物(BPLPs)。本文将讨论这些新型聚合物的合成、发展和应用,以及生物材料领域的当前趋势和未来发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recent Developments on Citric Acid Derived Biodegradable Elastomers
Biodegradable elastomers have recently found widespread application in many areas of biomedical engineering such as tissue engineering, drug delivery, and bioimaging. In particular, the recent developments in research have led to the creation of citric acid based polymers with enhanced mechanical properties, novel design strategies for crosslinking, nanoporous features, and unique photoluminescent capabilities. The present review will cover the recent patents involving citric acid derived biodegradable biomaterials within the field of biomedical engineering including poly (diol citrates) and their composites, crosslinked urethane-doped polyesters (CUPEs), poly (alkylene maleate citrates) (PAMCs), poly (xylitol-co-citrates) (PXC), and aliphatic biodegradable photoluminescent polymers (BPLPs). The synthesis, development, and applications of these novel polymers will be discussed along with the current trends and future developments in the biomaterials field.
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