A. Belousov, E. Malygon, V. Yavorskiy, E. Belousova
{"title":"利用纳米技术制备现代化红细胞保鲜液的新有效方法","authors":"A. Belousov, E. Malygon, V. Yavorskiy, E. Belousova","doi":"10.33140/ijnn.03.02.3","DOIUrl":null,"url":null,"abstract":"This study was devoted to the learning of the use of nanotechnology to correct the functional activity of red blood\ncells (RBCs) at the storage stages at a positive temperature. It was established that saline NaCl, which had previously\nbeen processed by magnetite nanoparticles (ICNB) had a marked membrane-stabilizing effect, inhibits hemolysis\nand increasing the sedimentation stability of preserved RBCs. The complex analysis of the obtained data allowed to\ndetermine the primary mechanisms effect of the saline NaCl, which had previously been processed by ICNB on the\npreserved RBCs. The proposed method of additive modernization of preserved RBCs was adapted to the production\nprocess. The optimization results were obtained in creating a simple and practical method of additive modernization\nof preservation solutions that does not violate the compliance requirements, improves the quality, efficiency and safety\ntransfusion of RBCs.","PeriodicalId":91888,"journal":{"name":"International journal of nanotechnology and nanomedicine","volume":"22 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":"{\"title\":\"The Creature of the New Effective Methods Modernization Preservative Solution for\\nRed Blood Cells by Means Preparations of Nanotechnology\",\"authors\":\"A. Belousov, E. Malygon, V. Yavorskiy, E. Belousova\",\"doi\":\"10.33140/ijnn.03.02.3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This study was devoted to the learning of the use of nanotechnology to correct the functional activity of red blood\\ncells (RBCs) at the storage stages at a positive temperature. It was established that saline NaCl, which had previously\\nbeen processed by magnetite nanoparticles (ICNB) had a marked membrane-stabilizing effect, inhibits hemolysis\\nand increasing the sedimentation stability of preserved RBCs. The complex analysis of the obtained data allowed to\\ndetermine the primary mechanisms effect of the saline NaCl, which had previously been processed by ICNB on the\\npreserved RBCs. The proposed method of additive modernization of preserved RBCs was adapted to the production\\nprocess. The optimization results were obtained in creating a simple and practical method of additive modernization\\nof preservation solutions that does not violate the compliance requirements, improves the quality, efficiency and safety\\ntransfusion of RBCs.\",\"PeriodicalId\":91888,\"journal\":{\"name\":\"International journal of nanotechnology and nanomedicine\",\"volume\":\"22 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-11-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of nanotechnology and nanomedicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33140/ijnn.03.02.3\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of nanotechnology and nanomedicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33140/ijnn.03.02.3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Creature of the New Effective Methods Modernization Preservative Solution for
Red Blood Cells by Means Preparations of Nanotechnology
This study was devoted to the learning of the use of nanotechnology to correct the functional activity of red blood
cells (RBCs) at the storage stages at a positive temperature. It was established that saline NaCl, which had previously
been processed by magnetite nanoparticles (ICNB) had a marked membrane-stabilizing effect, inhibits hemolysis
and increasing the sedimentation stability of preserved RBCs. The complex analysis of the obtained data allowed to
determine the primary mechanisms effect of the saline NaCl, which had previously been processed by ICNB on the
preserved RBCs. The proposed method of additive modernization of preserved RBCs was adapted to the production
process. The optimization results were obtained in creating a simple and practical method of additive modernization
of preservation solutions that does not violate the compliance requirements, improves the quality, efficiency and safety
transfusion of RBCs.