利用纳米技术制备现代化红细胞保鲜液的新有效方法

A. Belousov, E. Malygon, V. Yavorskiy, E. Belousova
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引用次数: 5

摘要

本研究致力于学习使用纳米技术来纠正红细胞(rbc)在正温度下储存阶段的功能活性。结果表明,经磁铁矿纳米颗粒(ICNB)处理过的盐水NaCl具有明显的膜稳定作用,可抑制溶血并提高保存红细胞的沉降稳定性。对获得的数据进行复杂的分析,可以确定盐水NaCl对保存的红细胞的主要机制影响,盐水NaCl先前已被ICNB处理过。提出的保存红细胞的添加剂现代化方法适用于生产过程。优化结果是创建了一种简单实用的保存溶液添加剂现代化方法,该方法不违反合规要求,提高了红细胞输血的质量、效率和安全性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Creature of the New Effective Methods Modernization Preservative Solution for Red Blood Cells by Means Preparations of Nanotechnology
This study was devoted to the learning of the use of nanotechnology to correct the functional activity of red blood cells (RBCs) at the storage stages at a positive temperature. It was established that saline NaCl, which had previously been processed by magnetite nanoparticles (ICNB) had a marked membrane-stabilizing effect, inhibits hemolysis and increasing the sedimentation stability of preserved RBCs. The complex analysis of the obtained data allowed to determine the primary mechanisms effect of the saline NaCl, which had previously been processed by ICNB on the preserved RBCs. The proposed method of additive modernization of preserved RBCs was adapted to the production process. The optimization results were obtained in creating a simple and practical method of additive modernization of preservation solutions that does not violate the compliance requirements, improves the quality, efficiency and safety transfusion of RBCs.
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