雌性大鼠青春期卵巢结构的组织学特征

N. A. Dudenkova, O. Shubina, V. S. Bardin
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摘要

我们研究的相关性是由于不孕症等女性疾病的高频率和患病率,这可能导致胎儿病理的各种发展。所有这些都可以被纳入生殖细胞的本质,但也出现在它们的形成和成熟过程中。本研究的目的是研究无产大鼠出生后卵巢的组织学参数。作为我们工作的研究对象,我们选用了2-3月龄、体重约200-250 g的该系雌性性成熟的白色大鼠。大鼠饲养于标准动物园内,不受病理影响。组织学检查的材料为绝经期卵巢。使用Axio成像仪检查涂片和组织样本。M2数码显微镜(蔡司,日本),配有AxioVision SE64 Rel图像分析软件。4.8.3和ZEN 2011。在我们的研究过程中,我们注意到在卵巢皮质的发丝阶段,卵泡处于不同的发育阶段:从原始卵泡到成熟的石墨泡。闭锁卵泡也可见。结缔组织间质是卵巢的基础,位于卵泡之间。雌性大鼠卵巢中可见黄色的月经体,通常在成熟卵泡排卵后形成。经期黄体在卵巢皮质物质中分布均匀。雌性大鼠卵巢结构的组织学特征证明实验动物性成熟。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
HISTOLOGICAL FEATURES OF THE STRUCTURE OF THE OVARIES OF FEMALE WHITE RATS DURING PUBERTY
The relevance of our study is due to the high frequency and prevalence of such a female disease as infertility, which can lead to various developments of fetal pathologies. All this can be incorporated in the very nature of germ cells, but also arise in the course of their formation and maturation. The aim of this study is to study the histological parameters of the ovaries of nulliparous white rats in the postnatal period. As an object of study in our work, we used female white sexually mature rats of the line at the age of 2–3 months and weighing about 200–250 g. The rats were kept in a standard vivarium and were not subjected to pathological effects. The material of histological examination was the ovaries at the stage of diestrus. Smears and tissue samples were examined using an Axio Imager.M2 digital microscope (ZEISS, Japan) with AxioVision SE64 Rel image analysis software. 4.8.3 and ZEN 2011. In the course of our studies, we noted that at the stage of diestrus in the ovarian cortex, follicles are at different stages of development: from primordial follicles and up to mature graphite vesicles. Atretic follicles are also revealed. The connective tissue stroma forms the basis of the ovary and is located between the follicles. In the ovaries of female white rats, yellow bodies of menstruation were found, which always form after ovulation of a mature mature follicle. The detected menstrual corpus luteum in the cortical substance of the ovary are evenly distributed. The revealed histological features of the structure of the ovaries of female white rats prove the sexual maturity of the experimental animals.
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