{"title":"神经肽Y低分子类似物对大鼠行为反应影响的研究","authors":"A. Zagayko, I. Havrylov, D. Lytkin","doi":"10.24959/cphj.19.1509","DOIUrl":null,"url":null,"abstract":"“elevated plus-maze”. Results. Experiments in rats showed the presence of anxiolytic properties of the compound without the associated sedative effect. In the tests “open field” and “elevated plus-maze”, the activating effect of the compound on the locomo-tor activity and a decrease in vegetative manifestations were observed. Conclusions. The data obtained indicate that the neuropeptide Y modified fragment is able to affect the anxiety level and research activity of rats; it substantiates the feasibility of further studies of this experimental compound.","PeriodicalId":10498,"journal":{"name":"Clinical pharmacy","volume":"17 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"The study of the effect of the low molecular analog of neuropeptide Y on behavioral reactions in rats\",\"authors\":\"A. Zagayko, I. Havrylov, D. Lytkin\",\"doi\":\"10.24959/cphj.19.1509\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"“elevated plus-maze”. Results. Experiments in rats showed the presence of anxiolytic properties of the compound without the associated sedative effect. In the tests “open field” and “elevated plus-maze”, the activating effect of the compound on the locomo-tor activity and a decrease in vegetative manifestations were observed. Conclusions. The data obtained indicate that the neuropeptide Y modified fragment is able to affect the anxiety level and research activity of rats; it substantiates the feasibility of further studies of this experimental compound.\",\"PeriodicalId\":10498,\"journal\":{\"name\":\"Clinical pharmacy\",\"volume\":\"17 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-11-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical pharmacy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24959/cphj.19.1509\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical pharmacy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24959/cphj.19.1509","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The study of the effect of the low molecular analog of neuropeptide Y on behavioral reactions in rats
“elevated plus-maze”. Results. Experiments in rats showed the presence of anxiolytic properties of the compound without the associated sedative effect. In the tests “open field” and “elevated plus-maze”, the activating effect of the compound on the locomo-tor activity and a decrease in vegetative manifestations were observed. Conclusions. The data obtained indicate that the neuropeptide Y modified fragment is able to affect the anxiety level and research activity of rats; it substantiates the feasibility of further studies of this experimental compound.