光生物调节疗法治疗灼口综合征的疗效观察

E. Bardellini, F. Amadori, G. Conti, A. Majorana
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引用次数: 20

摘要

本研究旨在评估光生物调节疗法(PBMT)在灼口综合征(BMS)患者疼痛和生活质量方面的疗效。材料与方法本研究为随机双盲前瞻性研究。研究招募了2015年6月至2018年6月期间诊断为BMS的患者。患者被随机分为两组,每组每周接受一次治疗,持续10周:a组接受激光治疗(K laser Cube 3®),B组接受假治疗(安慰剂)。通过视觉模拟量表(VAS)评估疼痛,通过口腔健康影响量表(OHIP-14)评估生活质量。评估在基线和每次治疗后进行。研究人员对随机分配一无所知。结果共分析85例患者。A组(激光治疗)43例,B组(假治疗)42例。接受PBMT治疗的患者症状显著减轻(p=0.0008),与口腔健康相关的生活质量得到改善(p=0.0002)。结论:PBMT已被证明在缓解BMS症状和改善患者整体生活质量方面具有积极作用。关键词:灼口综合征,口腔,激光,生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Efficacy of the photobiomodulation therapy in the treatment of the burning mouth syndrome
Background This study aims to evaluate the efficacy of the photobiomodulation therapy (PBMT) - in terms of pain and of quality of life- in patients affected by burning mouth syndrome (BMS). Material and Methods This study was designed as a randomised double-blinded prospective study. Patients diagnosed with BMS in the period from June 2015 to June 2018 were recruited. The patients were randomised into two groups and each received treatment once a week for ten weeks: group A received laser therapy (K Laser Cube 3®) while group B was given sham therapy (placebo). Pain was evaluated through the Visual Analogue Scale (VAS) and quality of life was assessed with the short form of the Oral Health Impact Profile (OHIP-14). Assessment was done at baseline and after every therapy session. The researchers were blind to the randomised allocations. Results A total of 85 patients were analysed. Group A (laser treatment) was composed of 43 patients while group B (sham therapy) of 42 patients. Patients treated with PBMT showed a significant decrease in symptoms (p=0.0008) and improved quality of life related to oral health (p=0.0002). Conclusions PBMT has demonstrated to have a positive effect in relieving BMS symptoms and in improving a patient’s overall quality of life. Key words:Burning mouth syndrome, oral cavity, lasers, life quality.
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