利用人诱导多能干细胞模型开发长QT综合征的诊断和治疗策略

Japanese Journal of Electrocardiology Pub Date : 2021-10-01 DOI:10.5105/jse.41.124

Daisuke Yoshinaga, T. Makiyama, Shiro Baba

{"title":"利用人诱导多能干细胞模型开发长QT综合征的诊断和治疗策略","authors":"Daisuke Yoshinaga, T. Makiyama, Shiro Baba","doi":"10.5105/jse.41.124","DOIUrl":null,"url":null,"abstract":"of patient-specific iPSC-CMs. This method may also be useful in diagnosing cases where pathogenic genetic mutations cannot be identified. In addition, iPSC-CMs are being studied as an experimental model for the development of therapies for hereditary arrhythmias. Here, we discuss the latest iPSC technologies related to hereditary arrhythmias.","PeriodicalId":14543,"journal":{"name":"Japanese Journal of Electrocardiology","volume":"34 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Development of Diagnostic and Therapeutic Strategy for Long QT Syndrome Using Human Induced Pluripotent Stem Cell Models\",\"authors\":\"Daisuke Yoshinaga, T. Makiyama, Shiro Baba\",\"doi\":\"10.5105/jse.41.124\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"of patient-specific iPSC-CMs. This method may also be useful in diagnosing cases where pathogenic genetic mutations cannot be identified. In addition, iPSC-CMs are being studied as an experimental model for the development of therapies for hereditary arrhythmias. Here, we discuss the latest iPSC technologies related to hereditary arrhythmias.\",\"PeriodicalId\":14543,\"journal\":{\"name\":\"Japanese Journal of Electrocardiology\",\"volume\":\"34 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Japanese Journal of Electrocardiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5105/jse.41.124\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese Journal of Electrocardiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5105/jse.41.124","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

患者特异性iPSC-CMs这种方法也可用于诊断致病性基因突变无法确定的病例。此外，iPSC-CMs正在作为遗传性心律失常治疗开发的实验模型进行研究。在此，我们讨论与遗传性心律失常相关的iPSC最新技术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Development of Diagnostic and Therapeutic Strategy for Long QT Syndrome Using Human Induced Pluripotent Stem Cell Models

of patient-specific iPSC-CMs. This method may also be useful in diagnosing cases where pathogenic genetic mutations cannot be identified. In addition, iPSC-CMs are being studied as an experimental model for the development of therapies for hereditary arrhythmias. Here, we discuss the latest iPSC technologies related to hereditary arrhythmias.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Japanese Journal of Electrocardiology

自引率

0.00%

发文量