{"title":"迈向阿尔茨海默病的生物学定义","authors":"A JellingerKurt","doi":"10.23937/2378-3001/1410095","DOIUrl":null,"url":null,"abstract":"Alzheimer disease (AD), the most common form of dementia, is a heterogenous syndrome with various pathobiologically defined subtypes. The clinical diagnosis of probable AD is enabled by the recent ATN biomarker system, but the definite diagnosis is only possible at post-mortem according to the updated NIA-AA criteria. The recent developments in the clinical and neuropathological diagnosis of AD including its specific subtypes improving the evaluation of AD and its impact on public health are briefly discussed.","PeriodicalId":14172,"journal":{"name":"International Journal of Neurology and Neurotherapy","volume":"113 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":"{\"title\":\"Towards a Biological Definition of Alzheimer Disease\",\"authors\":\"A JellingerKurt\",\"doi\":\"10.23937/2378-3001/1410095\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Alzheimer disease (AD), the most common form of dementia, is a heterogenous syndrome with various pathobiologically defined subtypes. The clinical diagnosis of probable AD is enabled by the recent ATN biomarker system, but the definite diagnosis is only possible at post-mortem according to the updated NIA-AA criteria. The recent developments in the clinical and neuropathological diagnosis of AD including its specific subtypes improving the evaluation of AD and its impact on public health are briefly discussed.\",\"PeriodicalId\":14172,\"journal\":{\"name\":\"International Journal of Neurology and Neurotherapy\",\"volume\":\"113 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Neurology and Neurotherapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23937/2378-3001/1410095\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Neurology and Neurotherapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23937/2378-3001/1410095","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Towards a Biological Definition of Alzheimer Disease
Alzheimer disease (AD), the most common form of dementia, is a heterogenous syndrome with various pathobiologically defined subtypes. The clinical diagnosis of probable AD is enabled by the recent ATN biomarker system, but the definite diagnosis is only possible at post-mortem according to the updated NIA-AA criteria. The recent developments in the clinical and neuropathological diagnosis of AD including its specific subtypes improving the evaluation of AD and its impact on public health are briefly discussed.
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