S. V. Shtyrkova, S. Shutov, P. A. Batrov, E. Rybakov, N. V. Prasolov
{"title":"a型血友病患者在Hartmann手术后取口合并FVIII抑制剂的产生(回顾与病例报告)","authors":"S. V. Shtyrkova, S. Shutov, P. A. Batrov, E. Rybakov, N. V. Prasolov","doi":"10.33878/2073-7556-2022-21-4-130-138","DOIUrl":null,"url":null,"abstract":"One of the specific manifestations of hemophilia A is the spontaneous abdominal hematoma mimicking the clinical picture of acute abdominal disease. The appearance of auto-antibodies to FVIII leads to a loss of response to replacement hemostatic therapy and requires an individualized approach as well as highly sensitive laboratory monitoring to reduce the risk of uncontrolled bleeding. The paper presents the case of multi-stage surgical treatment of this complication.","PeriodicalId":17840,"journal":{"name":"Koloproktologia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Stoma takedown after Hartmann’s procedure in a patient with hemophilia A complicated with production of inhibitor to FVIII (review and case report)\",\"authors\":\"S. V. Shtyrkova, S. Shutov, P. A. Batrov, E. Rybakov, N. V. Prasolov\",\"doi\":\"10.33878/2073-7556-2022-21-4-130-138\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"One of the specific manifestations of hemophilia A is the spontaneous abdominal hematoma mimicking the clinical picture of acute abdominal disease. The appearance of auto-antibodies to FVIII leads to a loss of response to replacement hemostatic therapy and requires an individualized approach as well as highly sensitive laboratory monitoring to reduce the risk of uncontrolled bleeding. The paper presents the case of multi-stage surgical treatment of this complication.\",\"PeriodicalId\":17840,\"journal\":{\"name\":\"Koloproktologia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-12-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Koloproktologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33878/2073-7556-2022-21-4-130-138\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Koloproktologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33878/2073-7556-2022-21-4-130-138","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Stoma takedown after Hartmann’s procedure in a patient with hemophilia A complicated with production of inhibitor to FVIII (review and case report)
One of the specific manifestations of hemophilia A is the spontaneous abdominal hematoma mimicking the clinical picture of acute abdominal disease. The appearance of auto-antibodies to FVIII leads to a loss of response to replacement hemostatic therapy and requires an individualized approach as well as highly sensitive laboratory monitoring to reduce the risk of uncontrolled bleeding. The paper presents the case of multi-stage surgical treatment of this complication.
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