儿童门静脉高压症的外科分流术:综述文章

V. Erikçi
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引用次数: 0

摘要

正常门静脉压力在0 ~ 10mmhg之间,门静脉压力略高于下腔静脉压力[1]。门脉高压(PH)通常定义为肝静脉压梯度大于5mmHg或肝静脉楔压大于10mmHg[2]。它通常是由慢性肝病和肝硬化引起的并发症。儿童PH的常见表现包括食道的灾难性静脉曲张出血。PH的其他常见临床特征包括脾肿大、脾功能亢进、腹水、脑病、肝肺综合征和门脉性肺动脉高压。据报道,高达15%的PH患儿最终需要进行分流手术[2]。传统上,分流手术是控制静脉曲张出血失败的儿童的治疗选择;吻合口狭窄或血栓发生率较高[1]。如今也有报道称,随着血管和移植手术的经验以及显微外科技术的提高,即使在幼儿中也可以取得良好的成功率[1]。在这篇综述文章中,目的是根据相关文献回顾儿童PH的手术治疗选择,特别是关于分流手术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgical Shunt Procedures in Childhood Portal Hypertension: A Review Article
Normal portal pressure is between 0 and 10 mmHg and the pressure in the portal vein is slightly higher than that of the pressure in the inferior vena cava [1]. Portal Hypertension (PH) is usually defined as either a hepatice venous pressure gradient greater than 5mmHg or hepatic venous wedge pressure greater than 10mmHg [2]. It is usually encountered as a complication arising from chronic liver disease and cirrhosis. Common presentation of PH in children include catastrophic variceal hemorrhage usually from esophagus. Other common clinical features of PH include splenomegaly, hypersplenism, ascites, encephalopathy, and hepatopulmonary syndrome and portopulmonary hypertension. It has been reported that up to 15% of children with PH ultimately require shunt surgery [2]. Traditionally shunt surgery was a treatment option for children in whom control of variceal bleeding failed however; it was associated with relatively high rate of anastomotic stricture or thrombosis [1]. Nowadays it has also been reported that as the experience in vascular and transplant surgery together with microsurgical techniques have improved good success rates can be achieved even in small children [1]. In this review article, it is aimed to review the surgical treatment options in children with PH with special regard to shunt procedures under the light of relevant literature.
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