植物性饮食预防慢性肾病的进展

Panigrahi Gunadhar
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引用次数: 1

摘要

慢性肾脏疾病(CKD)与高发病率、高死亡率相关,是医疗保健系统的昂贵负担[1,2]。CKD目前是美国第八大死因,影响了14%的美国人[3]。随着CKD的进展,心血管疾病死亡率上升,最终成为终末期肾病(ESRD)患者最常见的死亡原因[4,5]。人们对CKD的饮食治疗越来越感兴趣,以植物为基础的低蛋白素食饮食已被证明在治疗和减缓CKD进展方面是安全有效的[6]。这些患者接受了一个支架到RCA和另一个支架到LAD的治疗,血管造影结果良好,症状得到缓解。当时,她的药物包括Cozaar每日50毫克,Lopressor每日50毫克,每日2次,氢氯噻嗪每日25毫克,硝基贴剂每日2%局部涂抹,Zocor每日40毫克,非诺贝特每日134毫克,阿司匹林每日81毫克,Plavix每日75毫克,Neurontin每日100毫克。2014年3月13日,出院后,她来到我们的心血管健康诊所继续治疗。患者体重207磅(BMI 30.55 kg/m2),血压140/80 mm Hg,心率每分钟64次。脂质谱显示总胆固醇为254 mg/dl,甘油三酯为123 mg/dl, HDL胆固醇为51 mg/dl, LDL胆固醇为179 mg/dl。肾功能评估显示血尿素氮31 mg/dl,肌酐1.4 mg/dl, eGFR 44 ml/min/1.73 m2体表面积。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preventing Progression of Chronic Kidney Disease with Plant-Based Diet
Chronic kidney disease (CKD) is associated with high incidence of morbidity, mortality, and is a costly burden to the healthcare system [1,2]. CKD is now the 8th leading cause of death in the United States and affects 14% of its people [3]. As CKD progresses, cardiovascular mortality rises, eventually becoming the most common cause of death among end-stage renal disease (ESRD) patients [4,5]. There is a growing interest in the dietary treatment of CKD, and a Plant-Based low-protein vegetarian diet has shown to be safe and effective in both treating and in slowing the progression of CKD [6]. These were treated with a stent to RCA and another stent to LAD with excellent angiographic results, with resolution of symptoms. At that time, her medications included Cozaar 50 mg po daily, Lopressor 50 mg po twice daily, Hydrochlorothiazide 25 mg po daily, Nitro-patch 2% topically daily, Zocor 40 mg po daily, Fenofibrate 134 mg po daily, Aspirin 81 mg po daily, Plavix 75 mg po daily, Neurontin 100 mg po daily. On 3/13/2014, after discharge from hospital, she was seen in our Cardiovascular Wellness Clinic for continued care. She weighed 207 pounds (BMI 30.55 kg/m2), blood pressure was 140/80 mm of Hg, and heart rate was 64 beats per minute. The lipid profile revealed a total cholesterol of 254 mg/dl, triglyceride 123 mg/dl, HDL cholesterol 51 mg/dl, and LDL cholesterol were 179 mg/dl. Evaluation of renal function revealed blood urea nitrogen of 31 mg/dl and creatinine was 1.4 mg/dl, and eGFR of 44 ml/min/1.73 m2 of body surface area.
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