Dynamics of spontaneous heart rate turbulence in patients with pure chronic aortic regurgitation

Background: Biphasic responses to ventricular premature contractions (VPCs) cause heart rate turbulence (HRT), which is primarily mediated by the baroreceptors. HRT is useful for cardiovascular risk stratification of different cardiac diseases. Aim and objectives: The purpose of this research was to analyze HRT in patients with chronic Aortic regurgitation (AR) and determine whether there is a correlation between HRT parameters and echocardiographic data. Subjects and methods: This case control study was carried out in Specialized Medical Hospital, Cardiology Department, Mansoura University on 30 aortic regurgitation patients and other 30 control individuals. HRT parameters were compared in both groups. Result: There was a positive correlation between turbulence slope (TS) and ejection fraction (EF), Fractional shortening (FS). There was a positive correlation between turbulence onset (TO) and min heart rate (HR), and TS with time domain SDANN. Conclusion: Patients with chronic AR had significantly impaired HRT parameters compared to normal subjects.