The Quest of Happiness-Increase Happy Neurotransmitter Serotonin in the Brain

When discussing happiness, it’s worth noting that serotonin, a magical substance found in the body, is essential to achieving a state of well-being. Serotonin is a naturally occurring monoamine neurotransmitter that transmits signals between nerve cells throughout the body, contributing significantly to mood stabilization and supporting other bodily functions such as digestion, blood clotting, and sleep. When serotonin levels in the brain are low, it can cause changes in mood and disrupt sleep patterns, which can lead to depression. However, it’s important to note that although 95% of the serotonin in the body is produced in the gut, it cannot cross the “blood-brain barrier” and thus has no impact on emotional status. Increasing serotonin levels in the brain appears to enhance communication between brain cells, resulting in an uplifted mood and reduced depression symptoms. Prescription antidepressants like Selective Serotonin Reuptake Inhibitors (SSRIs) are frequently employed to treat clinical depression and other mood disorders by increasing serotonin levels in the brain via blocking the Serotonin reuptake process. The 5-HT system is also thought to be a connection between the circadian system, stress, and mood. 5-HT not only plays a part in generating non-photic phase shifts, but it also counteracts the effects of light in the SCN (Suprachiasmatic nucleus) . It has been found that food and exercise can increase serotonin levels in the brain. Thus SSRIs use can be minimized (Figure 1).