禽眼晶体的定量代谢组学数据集

IF 2.7 3区 物理与天体物理 Q2 PHYSICS, ATOMIC, MOLECULAR & CHEMICAL
E. Zelentsova, S. Mariasina, V. Yanshole, L. Yanshole, Nataliya A. Osik, K. Sharshov, Y. Tsentalovich
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引用次数: 0

摘要

代谢组学是一套强大的方法,它使用分析技术来识别和量化生物样品中的代谢物,提供生物系统代谢状态的快照。在医学上,代谢组学可以帮助揭示疾病的分子基础,做出诊断,并监测治疗反应,而在农业上,它可以提高作物产量和植物育种。然而,由于动物代谢组的复杂性和多样性,缺乏标准化的协议,以及难以解释代谢组学数据,动物代谢组学面临着一些挑战。目前的数据集包括26种鸟类(111个标本)的眼晶状体的定量代谢组学特征,可以帮助研究人员开发新的实验、数学模型,并与其他“组学”数据集成。该数据集包括原始1H NMR光谱,样品制备方案和数据预处理,最终表格包含89种可靠鉴定和量化代谢物的丰度信息。数据集是定量的,这使得它与补充新的标本或比较组相关,然后是数据挖掘和预期的新解释。数据采用符合伦理标准的鸟类标本获得,揭示了由于系统发育差异或环境暴露而导致的代谢途径的潜在差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quantitative Metabolomic Dataset of Avian Eye Lenses
Metabolomics is a powerful set of methods that uses analytical techniques to identify and quantify metabolites in biological samples, providing a snapshot of the metabolic state of a biological system. In medicine, metabolomics may help to reveal the molecular basis of a disease, make a diagnosis, and monitor treatment responses, while in agriculture, it can improve crop yields and plant breeding. However, animal metabolomics faces several challenges due to the complexity and diversity of animal metabolomes, the lack of standardized protocols, and the difficulty in interpreting metabolomic data. The current dataset includes quantitative metabolomic profiles of eye lenses from 26 bird species (111 specimens) that can aid researchers in developing new experiments, mathematical models, and integrating with other “-omics” data. The dataset includes raw 1H NMR spectra, protocols for sample preparation, and data preprocessing, with the final table containing information on the abundance of 89 reliably identified and quantified metabolites. The dataset is quantitative, making it relevant for supplementing with new specimens or comparison groups, followed by data mining and expected new interpretations. The data were obtained using the bird specimens collected in compliance with ethical standards and revealed potential differences in metabolic pathways due to phylogenetic differences or environmental exposure.
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来源期刊
Atomic Data and Nuclear Data Tables
Atomic Data and Nuclear Data Tables 物理-物理:核物理
CiteScore
4.50
自引率
11.10%
发文量
27
审稿时长
47 days
期刊介绍: Atomic Data and Nuclear Data Tables presents compilations of experimental and theoretical information in atomic physics, nuclear physics, and closely related fields. The journal is devoted to the publication of tables and graphs of general usefulness to researchers in both basic and applied areas. Extensive ... click here for full Aims & Scope Atomic Data and Nuclear Data Tables presents compilations of experimental and theoretical information in atomic physics, nuclear physics, and closely related fields. The journal is devoted to the publication of tables and graphs of general usefulness to researchers in both basic and applied areas. Extensive and comprehensive compilations of experimental and theoretical results are featured.
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