乳酸凝胶在治疗和预防细菌性阴道病和尿路感染中的应用是对抗菌治疗的挑战。文献综述

Q4 Medicine
A. D. Minakova, T. A. Dzhibladze, V. Zuev, I. Khokhlova
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引用次数: 0

摘要

细菌性阴道病和尿路感染是导致生活质量下降和重大经济成本的常见疾病。这篇综述提供了关于乳酸在阴道和泌尿道微生物群中的作用的最新信息,以及在这些情况下乳酸凝胶的使用。细菌性阴道病与尿路感染的风险增加有关。抗菌治疗在治疗恶化方面显示出统计学上显著的结果,但不能防止进一步的复发,这是由于细菌形成生物膜的能力可能很高。与过氧化氢不同,乳酸参与维持阴道微生物群并增强其对性传播感染的保护功能,并间接影响泌尿微生物群。这可能允许乳酸用于治疗和预防细菌性阴道病和尿路感染的复发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The use of a lactic acid gel in the treatment and prevention of bacterial vaginosis and urinary tract infections as a challenge to antibacterial therapy. A literature review
Bacterial vaginosis and urinary tract infections are common conditions that lead to a decrease in the quality of life and significant economic costs. The review provides up-to-date information on the role of lactic acid in the microbiota of the vagina and urinary tract, as well as on the use of a lactic acid gel in these conditions. Bacterial vaginosis is associated with an increased risk of urinary tract infections. Antibacterial therapy demonstrates statistically significant results in treating exacerbation, but not preventing further relapses, which is due to the possible high ability of bacteria to form biofilms. Lactic acid, unlike hydrogen peroxide, is involved in maintaining the vaginal microbiota and enhancing its protective function against sexually transmitted infections, and indirectly affects the urinary microbiota. This may allow the use of lactic acid for the treatment and prevention of relapses in both bacterial vaginosis and urinary tract infections.
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来源期刊
Journal of obstetrics and women's diseases
Journal of obstetrics and women's diseases Medicine-Obstetrics and Gynecology
CiteScore
0.40
自引率
0.00%
发文量
53
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