桃红提取物凝胶的防晒因子及化学稳定性的体外测定

Pratik P. Maske, Sachin G. Lokapure, Dhanashri Nimbalkar, Shobharaj Malavi, John I. D'souza
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引用次数: 29

摘要

目的研究玫瑰花瓣凝胶提取物的化学稳定性和体外防晒系数(SPF)。方法因其抗氧化和光防护的特性,在化妆品和药物制剂中具有广阔的应用前景。采用高效液相色谱法,在5℃、25℃和45℃条件下,以黄芩提取物为标记物,在3-4个月的时间内进行化学稳定性评价。用紫外分光光度法测定样品的防晒系数。结果在不同贮藏温度(5℃、25℃和45℃)下,以黄皮提取物的浓度测定黄皮提取物凝胶的化学稳定性。筛选黄芪提取物及其凝胶制剂的体外防晒因子,测定分离的黄芪提取物的光稳定性和SPF值。结论在5°C和25°C的低温条件下,冬青花瓣提取液凝胶的稳定性至少为3-4个月。这对于收集不同植物及其花以及其他部分的类似数据至关重要。这表明植物活性在抗太阳制剂中具有重要的预防作用。这将是一种更好、更便宜、更安全的替代品,可以替代目前行业中使用的有害化学防晒霜。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
In vitro determination of sun protection factor and chemical stability of Rosa kordesii extract gel

Aims

In the present study, to investigate its chemical stability and the in vitro sun protection factor (SPF) of Rosa kordesii petal extract in a gel formulation.

Methods

Due to its antioxidant and photoprotective properties, R. kordesii is a promising candidate for use in cosmetic and pharmaceutical formulations. A high performance liquid chromatography method was used to evaluate the chemical stability using R. kordesii extract as marker at 5, 25 and 45 °C for 3–4 months. The sun protection factors were analyzed by ultraviolet (UV) spectrophotometry using samples irradiated with UVB lamp.

Results

The chemical stability of the R. kordesii root extract gel was determined according to the concentration of R. kordesii extracts at different storage temperatures (5, 25 and 45 °C) for 3–4 months. It is screened for in vitro sun protection factor in the R. kordesii extract and of its gel formulation and determines Photostability of the isolated R. kordesii extract and SPF.

Conclusion

This study has shown that the R. kordesii petal extract gel is stable for at least 3–4 months when stored at 5 and 25 °C. It is essential for collection of similar data for different plants and their flowers, as well as other parts. This proved activity of plant showed its importance and prophylactic utility in anti-solar formulation. This will be a better, cheaper and safe alternative to harmful chemical sunscreens that used now a days in the industry.

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