Shawana Haque, M. Muttalib, A. Nesa, N. Uddin, S. Hossain, Thahamina Shahabuddin, A. Tasnim
{"title":"孟加拉国儿童和青少年1型糖尿病患者血清镁水平及其与血糖控制的关系","authors":"Shawana Haque, M. Muttalib, A. Nesa, N. Uddin, S. Hossain, Thahamina Shahabuddin, A. Tasnim","doi":"10.3329/BMJ.V48I3.51792","DOIUrl":null,"url":null,"abstract":"Type 1 diabetes mellitus is one of the most common endocrine and metabolic disorder in children and adolescents. Alteration of serum magnesium level may be associated with metabolic control and diabetic complications. The aim of the study was to evaluate serum magnesium level and find out its relationship with glycemic control in type 1 diabetic children and adolescents. For this study 80 type 1 diabetic children & adolescents with age range 1 to 18 years and 80 aged matched healthy controls were enrolled from the outpatient department of Changing Diabetes in Children, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine & Metabolic disorders, General Hospital, Dhaka. Using a cross sectional design, we measured anthropometric parameters and serum magnesium level of all study subjects. We also estimate the fasting plasma glucose and HbA1c levels of the diabetic children and adolescents and controls. The mean ± SD of serum magnesium level was significantly lower in patient with type 1 DM compared to control (0.7 ± 0.1 vs 0.8 ± 0.1 mmol/L respectively; p= < 0.001). Lower level of magnesium was found in subjects with poor glycemic control compared to good glycemic control (0.6 ± 0.1 vs 0.8 ± 0.1 mmol/L respectively; p= < 0.001). This study showed that serum magnesium level was lowered in type 1 diabetic children and adolescents and it was strongly associated with poor glycemic control which potentially contributing to the early development of diabetic complications. \nBangladesh Med J. 2019 Sep; 48 (3): 16-20","PeriodicalId":8711,"journal":{"name":"Bangladesh Medical Journal","volume":"16 1","pages":"16-20"},"PeriodicalIF":0.0000,"publicationDate":"2021-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Status of Serum Magnesium Level in Bangladeshi Children and Adolescents with Type 1 Diabetes Mellitus and its Relationship with Glycemic Control\",\"authors\":\"Shawana Haque, M. Muttalib, A. Nesa, N. Uddin, S. Hossain, Thahamina Shahabuddin, A. Tasnim\",\"doi\":\"10.3329/BMJ.V48I3.51792\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Type 1 diabetes mellitus is one of the most common endocrine and metabolic disorder in children and adolescents. Alteration of serum magnesium level may be associated with metabolic control and diabetic complications. The aim of the study was to evaluate serum magnesium level and find out its relationship with glycemic control in type 1 diabetic children and adolescents. For this study 80 type 1 diabetic children & adolescents with age range 1 to 18 years and 80 aged matched healthy controls were enrolled from the outpatient department of Changing Diabetes in Children, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine & Metabolic disorders, General Hospital, Dhaka. Using a cross sectional design, we measured anthropometric parameters and serum magnesium level of all study subjects. We also estimate the fasting plasma glucose and HbA1c levels of the diabetic children and adolescents and controls. The mean ± SD of serum magnesium level was significantly lower in patient with type 1 DM compared to control (0.7 ± 0.1 vs 0.8 ± 0.1 mmol/L respectively; p= < 0.001). Lower level of magnesium was found in subjects with poor glycemic control compared to good glycemic control (0.6 ± 0.1 vs 0.8 ± 0.1 mmol/L respectively; p= < 0.001). This study showed that serum magnesium level was lowered in type 1 diabetic children and adolescents and it was strongly associated with poor glycemic control which potentially contributing to the early development of diabetic complications. \\nBangladesh Med J. 2019 Sep; 48 (3): 16-20\",\"PeriodicalId\":8711,\"journal\":{\"name\":\"Bangladesh Medical Journal\",\"volume\":\"16 1\",\"pages\":\"16-20\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-02-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bangladesh Medical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3329/BMJ.V48I3.51792\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bangladesh Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3329/BMJ.V48I3.51792","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Status of Serum Magnesium Level in Bangladeshi Children and Adolescents with Type 1 Diabetes Mellitus and its Relationship with Glycemic Control
Type 1 diabetes mellitus is one of the most common endocrine and metabolic disorder in children and adolescents. Alteration of serum magnesium level may be associated with metabolic control and diabetic complications. The aim of the study was to evaluate serum magnesium level and find out its relationship with glycemic control in type 1 diabetic children and adolescents. For this study 80 type 1 diabetic children & adolescents with age range 1 to 18 years and 80 aged matched healthy controls were enrolled from the outpatient department of Changing Diabetes in Children, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine & Metabolic disorders, General Hospital, Dhaka. Using a cross sectional design, we measured anthropometric parameters and serum magnesium level of all study subjects. We also estimate the fasting plasma glucose and HbA1c levels of the diabetic children and adolescents and controls. The mean ± SD of serum magnesium level was significantly lower in patient with type 1 DM compared to control (0.7 ± 0.1 vs 0.8 ± 0.1 mmol/L respectively; p= < 0.001). Lower level of magnesium was found in subjects with poor glycemic control compared to good glycemic control (0.6 ± 0.1 vs 0.8 ± 0.1 mmol/L respectively; p= < 0.001). This study showed that serum magnesium level was lowered in type 1 diabetic children and adolescents and it was strongly associated with poor glycemic control which potentially contributing to the early development of diabetic complications.
Bangladesh Med J. 2019 Sep; 48 (3): 16-20