Md. Saifuzzaman , Md. Sarowar Jahan Shamim , Kamanashis Mahaldar , Eunus Sheemul Ali , Md. Amirul Islam
{"title":"荆芥醇提物的抗伤活性研究。","authors":"Md. Saifuzzaman , Md. Sarowar Jahan Shamim , Kamanashis Mahaldar , Eunus Sheemul Ali , Md. Amirul Islam","doi":"10.1016/j.jopr.2013.07.005","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p><em>Persicaria acuminata</em> Sach. (Family – Polygonaceae) commonly known as Bishkathali is a Bangladeshi native plant which is traditionally used in painful conditions.</p></div><div><h3>Objective</h3><p>The aim of the present study was to evaluate antinociceptive effect of the plant and to prove the scientific basis of traditional use.</p></div><div><h3>Methods</h3><p>The ethanolic extracts of leaf and stem of the plant were investigated using acetic acid induced writhing method on animal model.</p></div><div><h3>Results</h3><p>Oral administration of both leaf and stem extracts at the doses of 250 and 500 mg/kg body weight showed significant and dose-dependent inhibition of writhing response.</p></div><div><h3>Conclusion</h3><p>The study signifies the antinociceptive activity of the plant and supports its popular folkloric use in the management of pain.</p></div>","PeriodicalId":16787,"journal":{"name":"Journal of Pharmacy Research","volume":"6 7","pages":"Pages 753-755"},"PeriodicalIF":0.0000,"publicationDate":"2013-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jopr.2013.07.005","citationCount":"2","resultStr":"{\"title\":\"Antinociceptive activity of the ethanolic extract of Persicaria acuminata Sach.\",\"authors\":\"Md. Saifuzzaman , Md. Sarowar Jahan Shamim , Kamanashis Mahaldar , Eunus Sheemul Ali , Md. Amirul Islam\",\"doi\":\"10.1016/j.jopr.2013.07.005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p><em>Persicaria acuminata</em> Sach. (Family – Polygonaceae) commonly known as Bishkathali is a Bangladeshi native plant which is traditionally used in painful conditions.</p></div><div><h3>Objective</h3><p>The aim of the present study was to evaluate antinociceptive effect of the plant and to prove the scientific basis of traditional use.</p></div><div><h3>Methods</h3><p>The ethanolic extracts of leaf and stem of the plant were investigated using acetic acid induced writhing method on animal model.</p></div><div><h3>Results</h3><p>Oral administration of both leaf and stem extracts at the doses of 250 and 500 mg/kg body weight showed significant and dose-dependent inhibition of writhing response.</p></div><div><h3>Conclusion</h3><p>The study signifies the antinociceptive activity of the plant and supports its popular folkloric use in the management of pain.</p></div>\",\"PeriodicalId\":16787,\"journal\":{\"name\":\"Journal of Pharmacy Research\",\"volume\":\"6 7\",\"pages\":\"Pages 753-755\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.jopr.2013.07.005\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pharmacy Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S097469431300279X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pharmacy Research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S097469431300279X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Antinociceptive activity of the ethanolic extract of Persicaria acuminata Sach.
Background
Persicaria acuminata Sach. (Family – Polygonaceae) commonly known as Bishkathali is a Bangladeshi native plant which is traditionally used in painful conditions.
Objective
The aim of the present study was to evaluate antinociceptive effect of the plant and to prove the scientific basis of traditional use.
Methods
The ethanolic extracts of leaf and stem of the plant were investigated using acetic acid induced writhing method on animal model.
Results
Oral administration of both leaf and stem extracts at the doses of 250 and 500 mg/kg body weight showed significant and dose-dependent inhibition of writhing response.
Conclusion
The study signifies the antinociceptive activity of the plant and supports its popular folkloric use in the management of pain.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
