通过简易可重复使用口罩量化呼吸空气颗粒扩散控制

N. J. Edwards, Rebecca Widrick, R. Potember, Mike Gerschefske
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引用次数: 3

摘要

目的:确定非医用级可洗口罩或面罩控制空气传播(飞沫和气溶胶)的有效性,并有助于制定佩戴口罩的公共卫生策略,以减少COVID-19的传播。设计:本比较效果研究使用呼气模拟器进行94次实验,使用8种不同面料,5种口罩设计,以及说话和咳嗽的气流组合。设置:非密闭通风柜和多个激光散射粒子传感器。参与者:没有人类参与者。暴露:10% NaCl雾化溶液由呼气模拟器通过各种口罩和织物输送,呼气气流代表“咳嗽”和“说话或唱歌”。主要观察指标:主要观察指标为气溶胶扩散速度、颗粒数量的减少和扩散方向的改变。本研究使用的测量方法包括呼气流量峰(PEF)、气溶胶速度、曲线下浓度面积(AUC),以及两个新的呼气流量分散因子(EDF)和过滤效率指标(FEI)。结果:三因素方差分析表明,织物、口罩设计和呼气水平对改变方向、降低速度或浓度有统计学显著影响(织物:P = < 0.001, Wilks' {Lambda} = .000;口罩设计:P = < .001, Wilks' {Lambda} = .000;呼吸水平:P = < 0.001, Wilks' {Lambda} = 0.004)。所有主要因素组合之间也存在统计学上显著的相互作用效应。结论与意义:面罩或面罩的使用可显著减少空气中气溶胶颗粒的扩散。结果表明,佩戴非医用级可洗口罩或面罩有助于提高非药物干预措施(NPI)的有效性,特别是在共用空气空间中可能存在传染性污染物的情况下。然而,不同面料和口罩设计的效果差别很大。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quantifying Respiratory Airborne Particle Dispersion Control Through Improvised Reusable Masks
Objective: To determine the effectiveness of non-medical grade washable masks or face coverings in controlling airborne dispersion from exhalation (both droplet and aerosol), and to aid in establishing public health strategies on the wearing of masks to reduce COVID-19 transmission. Design: This comparative effectiveness study using an exhalation simulator to conduct 94 experiment runs with combinations of 8 different fabrics, 5 mask designs, and airflows for both talking and coughing. Setting: Non-airtight fume hood and multiple laser scattering particle sensors. Participants: No human participants. Exposure: 10% NaCl nebulized solution delivered by an exhalation simulator through various masks and fabrics with exhalation airflows representative of "coughing" and "talking or singing." Main Outcomes and Measures: The primary outcome was reduction in aerosol dispersion velocity, quantity of particles, and change in dispersion direction. Measurements used in this study included peak expiratory flow (PEF), aerosol velocity, concentration area under curve (AUC), and two novel metrics of expiratory flow dispersion factor (EDF) and filtration efficiency indicator (FEI). Results: Three-way multivariate analysis of variance establishes that factors of fabric, mask design, and exhalation breath level have a statistically significant effect on changing direction, reducing velocity or concentration (Fabric: P = < .001, Wilks' {Lambda} = .000; Mask design: P = < .001, Wilks' {Lambda} = .000; Breath level: P = < .001, Wilks' {Lambda} = .004). There were also statistically significant interaction effects between combinations of all primary factors. Conclusions and Relevance: The application of facial coverings or masks can significantly reduce the airborne dispersion of aerosolized particles from exhalation. The results show that wearing of non-medical grade washable masks or face coverings can help increase the effectiveness of non-pharmaceutical interventions (NPI) especially where infectious contaminants may exist in shared air spaces. However, the effectiveness varies greatly between the specific fabrics and mask designs used.
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