Seminal Vesicle Adenocarcinoma Associated with Zinner Syndrome: Case Report and Literature Review

The Zinner Syndrome is a rare congenital malformation represented by a triad of characteristics: ipsilateral renal agenesis, seminal vesicle cysts and ejaculatory duct obstruction. The aim of this study is to present a 69 year old man case, with seminal vesicle adenocarcinoma developed in association with Zinner Syndrome.First off all, patient presented with severe urinary retention. Had clinical and imaging examinations: ultrasound scan, computed tomography of the chest, abdomen and pelvis, abdominal-pelvic MRI and biochemical evaluation: PSA. As a result, diagnosis of Zinner Syndrome has been established and was suspected a carcinoma of seminal vesicle. The pacient underwent robotic removal of the tumoral cyst. The postoperative evolution of the patient was uneventful. The diagnosis of seminal vesicle adenocarcinoma was confirmed by immunohistochemistry, staining negative for PSA and positive for CK7. Seminal vesicle carcinomas are particularly rare. Their occurrence in patients with Zinner Syndrome is exceptional, but should be considered in differential diagnosis of pelvic tumors.