小麦(Triticum aestivum Linn.)的抗糖尿病、降血病和降胆固醇作用草汁代谢物治疗白化大鼠四氧嘧啶诱导的1型糖尿病

Sanjeev Kumar, K. Shachi, N. K. Prasad, N. Dubey, U. Dubey
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摘要

导读:自古以来,小麦草的治疗潜力就为人所知。在四氧嘧啶诱导的动物实验模型中,研究了小麦草汁的降血糖、降胆固醇和降血活性。材料和方法:将大鼠在实验室温度下驯化7 d。所有动物均饲喂标准水和颗粒饲料。用一水四氧嘧啶(120 mg/kg体重)诱导大鼠糖尿病。一水四氧嘧啶注射后,将大鼠分离,用小麦草汁和胰岛素治疗。血糖仪监测血糖水平。结果与讨论:与正常对照大鼠相比,糖尿病对照大鼠的空腹血糖和血清胆固醇水平明显升高。在给药后第7、14、21、28天观察小麦草汁对大鼠的降血糖、降胆固醇和降血活性。抗高血糖和抗胆固醇活性低于胰岛素治疗组。结论:希望本研究能为其在实验动物模型中的抗糖尿病、降血、降胆固醇作用奠定科学依据。结果有统计学意义(<0.05)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anti-diabetic, Haematinic and Anti-cholesterolmic Effects of Wheat (Triticum aestivum Linn.) Grass Juice Metabolites to Cure Alloxan Monohydrate induced type-1 Diabetes in Albino Rats
Introduction: From time immemorial therapeutic potential of Triticum aestivum grass is known. In present study an effort has been made to assess the hypoglycemic, anti-cholesterolmic and haematinic activity of Triticum aestivum grass juice in alloxan monohydrate induced experimental animal model. Materials and methods: Rats were acclimatized for 7 days in lab temperature. All animals were given standard water and pellet diet. Diabetes was induced in rats with the help of alloxan monohydrate (120 mg/kg body weight). After alloxan monohydrate injection rats were separated and treatment started with Triticum aestivum grass juice and insulin. Blood glucose level monitored with the help of glucometer. Results and discussion: A marked rise in fasting blood glucose as well as serum cholesterol level was observed in diabetic control rats when compared to normal control rats. Anti- hyperglycemic, anti-cholesterolmic and haematinic activity observed in Triticum aestivum grass juice administered rats on 7th, 14th, 21st and 28th days post treatment. Antihyperglycemic and anti-cholesterol mic activity was found less effective than that of insulin treatment group. Conclusion: It is hope that present investigation will be helpful in establishing a scientific basis for anti-diabetic, haematinic and anti- cholesterolmic effects in experimental animal models. The results are (<0.05) statistically significant.
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