{"title":"微胶囊化:大蒜(Allium sativum)粉末的味道和气味掩盖方法","authors":"S. Gondal, N. Abbas, A. Hussain","doi":"10.5920/BJPHARM.2017.19","DOIUrl":null,"url":null,"abstract":"The purpose of this study was to prepare a convenient formulation of garlic powder which has enhanced user compliance by suppressing its characteristic odour and masking the taste. Microcapsules of garlic powder were formulated by solvent evaporation method. Results show >80% yield, >70% drug loading efficiency and slow release profile (promising sustained action for more than 2hrs) and a significant reduction in the aromatic smell and taste evaluated through a single blind cross-over study conducted using ten healthy human volunteers.","PeriodicalId":9253,"journal":{"name":"British Journal of Pharmacy","volume":"9 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Microencapsulation: A taste and odour masking approach for garlic (Allium sativum) powder\",\"authors\":\"S. Gondal, N. Abbas, A. Hussain\",\"doi\":\"10.5920/BJPHARM.2017.19\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The purpose of this study was to prepare a convenient formulation of garlic powder which has enhanced user compliance by suppressing its characteristic odour and masking the taste. Microcapsules of garlic powder were formulated by solvent evaporation method. Results show >80% yield, >70% drug loading efficiency and slow release profile (promising sustained action for more than 2hrs) and a significant reduction in the aromatic smell and taste evaluated through a single blind cross-over study conducted using ten healthy human volunteers.\",\"PeriodicalId\":9253,\"journal\":{\"name\":\"British Journal of Pharmacy\",\"volume\":\"9 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-07-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British Journal of Pharmacy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5920/BJPHARM.2017.19\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British Journal of Pharmacy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5920/BJPHARM.2017.19","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Microencapsulation: A taste and odour masking approach for garlic (Allium sativum) powder
The purpose of this study was to prepare a convenient formulation of garlic powder which has enhanced user compliance by suppressing its characteristic odour and masking the taste. Microcapsules of garlic powder were formulated by solvent evaporation method. Results show >80% yield, >70% drug loading efficiency and slow release profile (promising sustained action for more than 2hrs) and a significant reduction in the aromatic smell and taste evaluated through a single blind cross-over study conducted using ten healthy human volunteers.