巴基斯坦一家大型三级医院的冠状动脉优势模式及其与冠状动脉疾病严重程度的关系

Ata ul Haiy, Tehreem K. Ramay, Roshaan Haider, Amna Shamim, S. A. Kazmi, M. A. Aslam, Nasiha Khalid
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引用次数: 1

摘要

背景:在心脏解剖学中,“支配”一词指的是后降支(PDA)的供应。因此,PDA可能起源于左旋动脉(LCX),右冠状动脉(RCA),或两者兼而有之,分别导致左显性(LD),右显性(RD)或共显性(CD)解剖。很少有研究探讨冠状动脉优势与冠状动脉疾病(CAD)严重程度的关系。CAD的严重程度根据狭窄程度定义为单侧、双侧或三侧血管病变。我们的研究旨在确定巴基斯坦的冠状动脉优势趋势,并显示冠状动脉优势与冠心病严重程度之间的相关性。方法:收集2018年6月17日至2018年8月4日期间巴基斯坦一家三级医院631例患者的冠状动脉造影数据。根据冠状动脉造影结果将患者分为LD、RD或CD。我们使用卡方和多项逻辑回归分析来评估冠状动脉显性与冠心病严重程度之间是否存在相关性。结果:患者RD为78.9%,LD为10.5%,CD为10.6%。CAD的显性程度与严重程度之间存在显著相关性,ꭕ2(8,N=631) = 17.58, p=0.025。右显性个体患三支血管疾病的几率大于单支血管(p =0.025;Or = 0.451;OR的95% CI: 0.224-0.906)和双血管疾病(p = 0.029;Or = 0.471;OR的95% CI: 0.239-0.926)。结论:在我们的研究中,右优势与冠状动脉疾病的严重程度呈正相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Patterns of Coronary Artery Dominance and Association with Severity of Coronary Artery Disease at a Large Tertiary Care Hospital in Pakistan
Background: In cardiac anatomy, the term "dominance" refers to the supply of the posterior descending artery (PDA). Therefore, the PDA might arise from the left circumflex artery (LCX), the right coronary artery (RCA), or both, resulting in left dominant (LD), right dominant (RD), or co-dominant (CD) anatomy, respectively.  Few studies have examined the relationship between coronary dominance and coronary artery disease (CAD) severity. CAD severity is defined as single, double, or triple vessel disease based on degree of stenosis.  Our study intends to identify coronary dominance trends in Pakistan and show a correlation between coronary dominance and the severity of CAD. Methods: Between Jun 17, 2018 and August 4, 2018 data from coronary angiographies of 631 patients at a tertiary care hospital in Pakistan was collected. Patients were classified as LD, RD, or CD as reported in the results of coronary angiograms. We utilized a chi-square and multinomial logistic regression analyses to assess whether a correlation exists between coronary dominance and CAD severity. Results: Subjects were 78.9% RD, 10.5% LD, and 10.6% CD. A significant relation between dominance and severity of CAD was noted, ꭕ2(8, N=631) = 17.58, p=0.025. Individuals with right dominance had a greater chance of developing triple-vessel disease than single-vessel (p =0.025; OR = 0.451; 95% CI for OR: 0.224–0.906) and two-vessel disease (p = 0.029; OR = 0.471; 95% CI for OR: 0.239–0.926). Conclusion: In our study, right dominance has a positive correlation with severity of coronary artery disease.
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