A COMPARATIVE STUDY OF GUDUCHYADI VATI IN THE MANAGEMENT OF GARBHASRAVA PURVARUPAVASTHA/THREATENED ABORTION

Pregnancy bring a new meaning to the concept of beauty. It is the period of immense joy coupled with excitements. Threatened abortion is the most common complication which occurs during pregnancy particularly in first trimester. Present data suggests that 30-60% of fertilized embryos fails to implant and out of implanted embryos 25% suffers early pregnancy loss mostly in first 6 weeks of pregnancy. In threatened abortion bleeding occurs through closed cervical OS. Further if bleeding continues it may land up in incomplete or complete abortion. And if pregnancy continues it may cause intra uterine growth retardation and other complications. Every system of medicine work to cure disease but Ayurveda helps to improve complete health both physically and mentally as well as helps to get rid of various diseases. So, Ayurveda maintain a respectable status among all system of medicine for conserving good health. Aim and Objective: To compare the efficacy of Guduchyadi vati with micronized progesterone in management of Garbhasrava/ threatened abortion. Material and Methods: Total 72 patients of Garbhasrava Purvarupavastha were studied by dividing randomly in two groups who are fulfilling the inclusive criteria. Selection of patients was done from Department of Stree Roga and Prasuti Tantra OPD. Results: The efficacy of the drug was evaluated according to the relief in signs and symptoms after the treatment was completed. In trial group, in all the symptoms like PV bleeding, size of sub chorionic hematoma, abdominal pain, back pain, generalized weakness and fatigue statistical analysis showed highly significant difference between before and after treatment. Size of sub chorionic hematoma was observed sonographically BT and AT. Also, in another group, in which progesterone was given showed significant improvement in signs and symptoms of threatened abortion. Discussion and Conclusion: The symptomatic parameters were compared and analyzed statistically by Mann Whitney’s U test in both the groups which concluded that Guduchyadi Vati and progesterone both are effective in prevention of threatened abortion but Guduchyadi Vati is more effective in reducing associated symptoms then progesterone.