触觉按摩或放松运动不能改善2型糖尿病患者的代谢控制

P. Wändell, A. Carlsson, K. Andersson, C. Gåfvels, L. Tornkvist
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引用次数: 15

摘要

一项初步研究显示,糖尿病患者通过触觉按摩(TM)可使糖化血红蛋白(血红蛋白A1c)降低0.8%。本研究在初级卫生保健中心的2型糖尿病患者中进行,作为一项平行临床研究,进行意向治疗分析,每周进行一次TM (n=26)或每周进行一次cd放松(n=27),为期10周。测量患者的体重、身高、腰围,计算BMI,抽血(p -葡萄糖、B-HbA1c、fs -胰岛素、高敏P-CRP、s - tnf - α、s -白细胞介素-6、s -脂联素、s -瘦素、fP-Ghrelin),收集24小时尿液中儿茶酚胺和皮质醇的含量,并在基线、干预10周后和干预后3个月随访时填写包括生活方式变量在内的问卷。舒张组和TM组HbA1c均无明显变化。两组患者腰围均减小(p=0.01),但以TM组最大,两组校正后差异为4.0 cm(95%可信区间1.6 ~ 6.4 cm)。TM组s -脂联素水平显著升高(p=0.0095)。TM疗法不推荐作为2型糖尿病患者的一般治疗方法。然而,对高感知压力水平患者和其他患者群体的进一步研究可能是有价值的。腰围减少的意义尚不清楚,但从长远来看可能有一定的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tactile Massage or Relaxation Exercises Do Not Improve the Metabolic Control of Type 2 Diabetics~!2009-12-22~!2010-03-25~!2010-04-28~!
A 0.8% reduction in glycosylated hemoglobin (hemoglobin A1c) by tactile massage (TM) in patients with diabetes has been shown in a pilot study. The present study was carried out in patients with type 2 diabetes at primary healthcare centers as a parallel-arm clinical study with intention-to-treat analysis, of 10 weeks of TM once/week (n=26) or relaxation using a compact disc once/week (n=27). Anthropometrics were measured, i.e. weight, height, waist and calculation of BMI, blood samples were drawn, i.e. fP-glucose, B-HbA1c, fS-insulin, high-sensitive P-CRP, S-TNF-alpha, S-Interleukin-6, S-Adiponectin, S-Leptin and fP-Ghrelin, urine was collected for 24 hours for catecholamines and cortisol, and questionnaires including lifestyle variables were completed at baseline, after the 10-week intervention and at a follow- up 3 months after the intervention. There was no significant change in HbA1c in either the TM or the relaxation group. Waist circumference was reduced in both groups (p=0.01) but mostly in the TM group, with an adjusted difference between the groups of 4.0 cm (95% confidence interval 1.6-6.4 cm). The S-Adiponectin level increased significantly in the TM group (p=0.0095). TM therapy could not be recommended as a general treatment in subjects with type 2 diabetes. However, further studies in patients with high perceived level of stress and in other patient groups could be of value. The significance of the reduced waist is unclear, but could be of some importance in the long run.
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