New rapid diagnostic tests for HIV infection

Technological advances in the diagnosis of human immunodeficiency virus (HIV) infection provide the clinician with greater opportunities to reduce HIV transmission rates. The main drawback of conventional methods of HIV testing is a potential delay of 1–2 weeks for obtaining results, making routine screening a two-step method. Many of those tested never return to learn of their results, limiting our efforts to notify seropositive individuals and their contacts. Consequently, our ability to educate them on strategies for optimizing their health and reducing their risk for transmitting the disease is impaired. For pregnant women who present to Labor and Delivery with late prenatal care, having unknown HIV serological status reduces our ability to prevent transmission to neonates. Two new rapid HIV tests have become available commercially. These tests are just as accurate as conventional methods and offer the advantage of producing preliminary results within hours rather than days. As a result, case- finding and prevention counseling can be completed in a single visit, making the process more efficient and, hopefully, more effective. Additionally, faster identification of seropositive pregnant women who present later for prenatal care allows us to more precisely target intrapartum antiretroviral therapy for prevention of vertical HIV transmission.