Ekaterina A. Ruina, Ekaterina A. Aleksandrova, Elena V. Parshina, Danil N. Rodygin, V. S. Yulin
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引用次数: 0
摘要
通过对俄罗斯和国外医学文献以及Web of Science、PubMed和Scopus数据库的回顾,发现8例多发性硬化症和帕金森病共存。帕金森病是一种由黑质多巴胺能神经元退化引起的慢性进行性神经系统疾病。多发性硬化症是一种慢性脱髓鞘疾病,在这种疾病中,一系列自身免疫驱动的炎症和神经退行性过程导致中枢神经系统形成许多局灶性和弥漫性病变,导致残疾和患者生活质量显著下降。这两种神经退行性中枢神经系统疾病同时发生在临床上是很少见的。作者描述了一个临床病例,以证明他们的方法来诊断和管理这个病人组。
Rare co-occurrence of multiple sclerosis and Parkinson's disease: a case report
A review of Russian and foreign medical literature, as well as the Web of Science, PubMed and Scopus databases, revealed 8 cases of multiple sclerosis and Parkinson's disease co-occurrence. Parkinson's disease is a chronic, progressive neurological disease caused by degeneration of dopaminergic neurons in the substantia nigra. Multiple sclerosis is a chronic demyelinating disease, in which a range of autoimmune-driven inflammatory and neurodegenerative processes lead to formation of numerous focal and diffuse lesions in the central nervous system, resulting in disability and a significant decrease in patient quality of life. The co-occurrence of these two neurodegenerative CNS disorders is rarely seen in clinical practice.
The authors describe a clinical case to demonstrate their approach to the diagnosis and management of this patient group.