新病毒的分子研究及其与玫瑰糠疹的关系。

Ahmed Abdulhussein Kawen
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引用次数: 0

摘要

2020年3月11日,新型冠状病毒家族严重急性呼吸综合征冠状病毒-2 (SARS-CoV-2)在有几种临床症状的个体中被发现,被称为COVID-19,被确认为大流行。关于与COVID-19相关的皮肤病的表现,即皮疹或玫瑰糠疹(PR),血管标记和丘疹样病变,已有大量研究。本研究旨在了解冠状病毒是否会影响PR的发展,这也可以被认为是其他类型感染的触发和症状。材料和方法本研究是一个病例系列,描述了在卡塔尔省与COVID-19相关的皮肤病学发现。样本取自侯赛因教学医院的住院病人、门诊病人、急诊科和谢法阿隔离医院的住院病人。该研究历时4个月(2020年6月至9月)。结果本研究共纳入冠状病毒感染合并PR患者19例,其中女性10例(52.6%),男性9例(47.4%)。按典型和异常方式的PR发生率分布分别为77.9%和21.1%。PR发病率最高的是中度肺炎(84.2%),轻度肺炎(15.8%)。按性别划分的平均年龄分布差异无统计学意义,按PR和COVID-19类别划分的平均年龄分布差异有统计学意义。需要更多的研究来评估这些病变是否与病毒有关。结论PR是COVID-19的皮肤病学发现之一,根据患者背景和COVID-19的严重程度,PR在疾病分布中没有明确的作用。它可以由COVID-19引发,并随着疾病的清除而完全治愈。建议需要与COVID-19相关的准确而有力的皮肤记录,以提高对该疾病及其流行病学的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Molecular study of recent virus and its relationship to Pityriasis rosea.
BACKGROUND A new type of coronavirus family severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that has been detected in individuals with several clinical symptoms named COVID-19, was recognized as a pandemic on March 11, 2020. Numerous researches have been conducted on the manifestations of a skin disease related to COVID-19, i.e., rashes or Pityriasis rosea (PR), vascular markings, and pimple-like lesions. AIM This study aims to find out if the Coronavirus can affect the PR development, which also can be considered as a trigger and symptom for other types of infections. MATERIAL AND METHODS This study is a case series describing the dermatological findings related to COVID-19 in the Thi-Qar Governorate. Samples were taken from inpatients, outpatients, and from the emergency unit of Al Hussein Teaching Hospital, and inwards of Al-Shefaa' Isolation Hospital. The study has been done over a 4 month period (June-September, 2020.). RESULTS Around 19 patients, 10 females (52.6%) and 9 males (47.4%), who were infected with Coronavirus and were suffering from PR, are included in this study. The distribution of patients according to the incidence of PR in typical and anomalous manners were 77.9% and 21.1% respectively. The highest percentage of the incidence of PR was in moderate COVID-19 (84.2%), while it was around 15.8% in mild COVID-19. There was no significant statistical difference in the mean age distribution according to gender, while there was a significant statistical difference according to PR and COVID-19 class. More studies are needed to evaluate whether or not these lesions are associated with the virus. CONCLUSION The PR was one of the dermatological finding of COVID-19 that did not have a clear role in the distribution of the disease according to the background of the patients, and also the severity of COVID-19. It can be triggered by COVID-19 and be completely cured with the clearance of the disease. RECOMMENDATION An accurate robust cutaneous documentation related to COVID-19 is required to improve the knowledge of the disease as well as its epidemiology.
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