三齿ONO席夫碱配体Cu(II)配合物的光谱分析及体外生物活性

E. Horozić, M. Ibišević, D. Husejnagić, Enida Karić, N. Hasić, Amina Hajdarević
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引用次数: 0

摘要

本文以2,2-二羟基茚-1,3-二酮和2-氨基乙醇酸为原料,合成了含席夫碱的金属配合物铜(II)。用光谱方法对产物进行了表征。对参比菌株进行抑菌活性测定,并采用DPPH法和FRAP法分析其抗氧化能力。光谱数据表明,席夫碱与铜(II)配位为三齿ONO给体配位。这些化合物对某些微生物的抑菌活性较弱。体外抗氧化活性测试表明,该复合物具有显著的还原能力,以及对DPPH自由基的抑制活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spectral Analysis and In vitro Biological Activity of Cu(II) Complex with Tridentate ONO Schiff Base Ligand
In this study, metal complex of Copper(II) with a Schiff base derived from 2,2-dihydroxyindane-1,3-dione and 2-aminoethanoic acid were synthesized. The product are characterized by spectral methods. The antimicrobial activity was tested on reference bacterial strains and the antioxidant capacity was analyzed by using the DPPH and FRAP methods. The spectral data indicates that the Schiff base coordinates the Copper(II) as a tridentate ONO donor ligand. The compounds showed weaker antimicrobial activity on certain tested microorganisms. In vitro testing of antioxidant activity showed a significant reducing ability of the complex, as well as inhibitory activity against DPPH radicals.
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