基于微波的诊疗实践

M. Persson, A. Fhager, H. Trefná, P. Takook, Yinan Yu, T. McKelvey, J. Karlsson, X. Zeng, H. Zirath, M. Elam
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引用次数: 3

摘要

全球每年约有1500万人患中风。只有一小部分可以受益于溶栓治疗的脑卒中患者能够及时得到诊断和治疗。为了提高这个低数字,我们开发了微波技术,旨在区分出血性和缺血性脑卒中患者。目前诊断乳腺癌的标准方法是x射线乳房x光检查。尽管它具有检测肿瘤的公认能力,但它仍有一些局限性。假阳性和假阴性检出率都不容忽视。目前正在广泛研究的一个有趣的替代方法是微波断层扫描。在我们目前努力开发临床原型的过程中,我们发现最合适的设计包括以全3D模式放置的天线阵列。在过去的十年中,临床研究已经证明微波热疗能够显著提高癌症患者的生存率。最根本的挑战是在充分加热深层肿瘤的同时,防止周围的健康组织受到不必要的加热和损伤。我们正在专门解决提供具有空间控制,患者治疗计划和非侵入性温度测量的功率水平的挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microwave based diagnostics and treatment in practice
Globally, around 15 million people each year suffer a stroke. Only a small fraction of stroke patients who could benefit from thrombolytic treatment reach diagnosis and treatment in time. To increase this low figure we have developed microwave technology aiming to differentiate hemorrhagic from ischemic stroke patients. The standard method for breast cancer diagnosis today is X-ray mammography. Despite its recognized ability to detect tumors it suffers from some limitations. Neither the false positive nor the false negative detection rates are negligible. An interesting alternative being researched extensively today is microwave tomography. In our current strive to develop a clinical prototype we have found that the most suitable design consists of an antenna array placed in a full 3D pattern. During the last decade clinical studies have demonstrated the ability of microwave hyperthermia to dramatically enhance cancer patient survival. The fundamental challenge is to adequately heat deep-seated tumors while preventing surrounding healthy tissue from undesired heating and damage. We are specifically addressing the challenge to deliver power levels with spatial control, patient treatment planning, and noninvasive temperature measurements.
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