Preliminary Clinical Study of Initial Screening Blood Test Data onOutpatients with Burning Mouth Syndrome

Study background: The objective of study is a survey to report the prevalence of burning mouth syndrome (BMS) and to evaluated the co-morbidities associated to BMS. Subjects and Methods: A total 393 patients (54 males and 339 females; mean age 67 years; age range 27-102) were selected for this study. We carried out initial screening blood tests to these patients. Furthermore, we examined if there were previous and/or present systemic diseases and regularly taken medication by medical interview. Results: Female patients over 50 years old accounted for 89.3% (351/393). Dry mouth (330/393: 84.0%) was the most concomitant symptom with BMS. The ratio of abnormal measurements of iron was 35.9% (141/393). Zinc was 12.2% (48/393). However, the higher outrange ratio of MCV was 39.9% (157/393) and the lower outrange ratio of MCV was 8.7% (34/393). The higher outrange ratio of MCH was 36.6% (144/393) and the lower outrange ratio of MCH was 6.4% (25/393). The highest ratio of systematic disease of hypertension was 34.6% (136/393). Conclusions: We suspected that pernicious anemia may be most important factor of the BMS. Many patients had a number of systemic diseases and were taking several kinds of medicine. BMS is very complex disease, so it needs that more detailed investigation of systematic disease and habitual drug-taking is also needed.