经皮经肝生物可降解胆道支架置入术治疗良性胆道狭窄

Shaima Abulqasim, M. Arabi, K. Almasar, Bayan A. Albdah, Refaat Salman
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摘要

摘要本文旨在评价生物可降解支架治疗良性胆道狭窄的安全性和有效性。这是一项回顾性观察性研究,纳入了2016年7月至2019年8月期间因胆道狭窄良性原因植入生物可降解支架的所有成年患者。纳入19例患者。17例患者接受了肝移植。1例患者因原发性硬化性胆管炎行肝空肠吻合术,1例患者因医源性左主胆管闭塞。所有19例患者均成功放置支架(技术成功率:100%)。6个月通畅率为90%(17/19),12个月通畅率为80%(12/15)。研究中有7例患者狭窄复发,需要再干预,平均再干预时间为418天(范围:8 - 1155天)。有一个主要的并发症是胆管炎和败血症,这需要用哌拉西林/他唑巴坦治疗10天。无手术相关胰腺炎或死亡发生。可生物降解支架是一种安全有效的治疗良性胆道狭窄的选择,可以实现长期通畅而无需再干预。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Percutaneous Transhepatic Biodegradable Biliary Stent Placement for Benign Biliary Strictures
Abstract This article aimed to assess the safety and effectiveness of biodegradable stents in the management of benign biliary strictures. This is a retrospective observational study that included all adult patients who had biodegradable stent placement for a benign cause of biliary stricture between July 2016 and August 2019. Nineteen patients were included. Seventeen patients had liver transplant. One patient had hepaticojejunostomy due to primary sclerosing cholangitis and one patient had iatrogenic left main bile duct occlusion. Stents were successfully deployed in all 19 patients (technical success: 100%). Patency rate was 90% (17/19) at 6 months and 80% (12/15) at 12 months. Seven patients in the study had stricture recurrence and needed reintervention with mean time to reintervention of 418 days (range: 8–1,155 days). There was one major complication due to cholangitis and sepsis, which required a treatment course with piperacillin/tazobactam for 10 days. No procedure-related pancreatitis or deaths occurred. Biodegradable stents are a safe and effective treatment option for benign biliary strictures and can achieve long-term patency without the need for reinterventions.
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