口腔电影的文献综述

Yarragunta Roja, Hindustan Abdul Ahad, Haranath Chinthaginjala, Maninjeri Soumya, Sana Muskan, Nagaraju gari Kavyasree
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引用次数: 1

摘要

本文主要研究颊部膜。它是一种增强活性药物成分的安全性、有效性和稳定性的buccoadhesive给药系统。颊膜是一种新颖的技术,因为它可以更好地优化治疗效果。该给药系统适用于通过高首过代谢并用于提高生物利用度的药物。所述口腔膜可配制为溶剂铸造、半固体铸造、热熔挤压、固体分散或轧制方法。其中,多采用溶剂铸造法。评估口腔膜的机械性能,即感官评估、厚度、干燥度、粘性测试、拉伸强度、伸长率、折叠耐久性、膨胀资产、表面pH值、接触角、透明度、药物含量均匀性、崩解和体外溶出测试。这篇文章给出了一些关于口腔电影过去工作的文献。这篇文章有助于快速参考到目前为止在口腔电影上所做的早期尝试。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Glance at the Literature review on Buccal films
The present article concentrates on the Buccal film. It is a buccoadhesive drug delivery system that enhances the safety, efficacy, and stability of active pharmaceutical ingredients. The buccal film is a novel technology due to its better option to optimize therapeutic efficacy. This drug delivery system is suitable for drugs that pass through high first-pass metabolism and are used for enhancing bioavailability. The buccal film can be formulated as a solvent casting, semi-solid casting, hot-melt extrusion, solid dispersion, or rolling method. Among them, the solvent casting method is mostly adopted. The buccal films are evaluated for mechanical properties viz., Organoleptic assessment, thickness, dryness, tack test, tensile strength, percent elongation, folding endurance, swelling assets, surface pH, contact angle, transparency, uniformity in drug content, disintegration, and in-vitro dissolution tests. The article gave a handful of literature on past work done on buccal films. This article helps with quick references to the earlier attempts so far made on buccal films.
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