乳糜泻表现为弥漫性肺泡出血和心脏传导阻滞

Respiratory Medicine Extra Pub Date : 2006-01-01 DOI:10.1016/j.rmedx.2006.06.001

Vincent Cottin , Gael Clérici , Nicole Fabien , Hugues Rousset , Jean-François Cordier

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引用次数: 5

摘要

背景乳糜泻是一种常见的疾病，其特征是对摄入的小麦面筋产生免疫反应。它可能与肺或心脏表现有关。MethodsCase报告。结果52岁女性，有慢性贫血病史，以弥漫性肺泡出血和房室传导阻滞为主。乳糜泻的诊断是基于抗转谷氨酰胺酶、抗肌内膜和抗麦胶蛋白抗体阳性，以及空肠活检显示完全绒毛萎缩。结论弥漫性肺泡出血患者应采用抗转谷氨酰胺酶抗体筛查乳糜泻。有乳糜泻或肺泡出血的患者需要心电图检查。

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Celiac disease revealed by diffuse alveolar hemorrhage and heart block

Background

Celiac disease is a common disorder characterised by an immune response to ingested wheat gluten. It may be associated with pulmonary or cardiac manifestations.

Methods

Case report.

Results

A 52-year old woman with a history of chronic anemia presented with diffuse alveolar hemorrhage and atrioventricular heart block. The diagnosis of celiac disease was based on positive anti-transglutaminase, anti-endomysial, and anti-gliadin antibodies, and on jejunal biopsies showing complete villous atrophy.

Conclusion

Screening for celiac disease using anti-transglutaminase antibodies should be performed in patients with diffuse alveolar hemorrhage. Electrocardiogram is warranted in patients with celiac disease or alveolar hemorrhage.

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来源期刊

Respiratory Medicine Extra

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