{"title":"评价脑脊液乳酸脱氢酶对意识水平下降患者中枢神经系统结构性和非结构性病变的鉴别价值。","authors":"Dr.Yogesh Kumar, Dr.Jyoti Prakash Yogi, Dr.Sumanta Banerjee","doi":"10.9790/0853-1606142830","DOIUrl":null,"url":null,"abstract":"Although both metabolic and structural abnormalities have devastating effect on the CNS, their treatment approaches and prognoses vary considerably. This study was conducted among 53 patients with diminished level of consciousness and CSF was analyzed for quantitative LDH(IU/L) value. In our study mean CSF-LDH was 25.19 ± 12.92 in patients with non-structural lesion and 86.53 ± 32.09 in patients with structural lesion of brain and difference was statistically highly significant (p<0.001). So CSF-LDH values can be used to differentiate between patients with structural pathology and those with metabolic disturbances.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Assessment of Lactic Dehydrogenase in Cerebrospinal Fluid to Differentiate Between Structural And Non-Structural Central Nervous System Lesions in Patients with Diminished Level of Consciousness.\",\"authors\":\"Dr.Yogesh Kumar, Dr.Jyoti Prakash Yogi, Dr.Sumanta Banerjee\",\"doi\":\"10.9790/0853-1606142830\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Although both metabolic and structural abnormalities have devastating effect on the CNS, their treatment approaches and prognoses vary considerably. This study was conducted among 53 patients with diminished level of consciousness and CSF was analyzed for quantitative LDH(IU/L) value. In our study mean CSF-LDH was 25.19 ± 12.92 in patients with non-structural lesion and 86.53 ± 32.09 in patients with structural lesion of brain and difference was statistically highly significant (p<0.001). So CSF-LDH values can be used to differentiate between patients with structural pathology and those with metabolic disturbances.\",\"PeriodicalId\":14489,\"journal\":{\"name\":\"IOSR Journal of Dental and Medical Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IOSR Journal of Dental and Medical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.9790/0853-1606142830\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IOSR Journal of Dental and Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9790/0853-1606142830","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Assessment of Lactic Dehydrogenase in Cerebrospinal Fluid to Differentiate Between Structural And Non-Structural Central Nervous System Lesions in Patients with Diminished Level of Consciousness.
Although both metabolic and structural abnormalities have devastating effect on the CNS, their treatment approaches and prognoses vary considerably. This study was conducted among 53 patients with diminished level of consciousness and CSF was analyzed for quantitative LDH(IU/L) value. In our study mean CSF-LDH was 25.19 ± 12.92 in patients with non-structural lesion and 86.53 ± 32.09 in patients with structural lesion of brain and difference was statistically highly significant (p<0.001). So CSF-LDH values can be used to differentiate between patients with structural pathology and those with metabolic disturbances.
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