太赫兹生物学:研究溶液中的蛋白质动力学

Infrared and Millimeter Waves, Conference Digest of the 2004 Joint 29th International Conference on 2004 and 12th International Conference on Terahertz Electronics, 2004. Pub Date : 2004-12-01 DOI:10.1109/ICIMW.2004.1422300

M. Havenith, U. Heugen, A. Bergner, S. Ebbinghaus, E. Brundermann, E. Larios, D. Leitner, M. Gruebele

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引用次数: 2

摘要

研制了太赫兹光谱仪，用于测量溶剂化蛋白质的吸收光谱。辐射源是一个p型锗激光器，在太赫兹范围内(从1-4太赫兹)提供数瓦的输出功率。以泛素和/spl λ /-阻遏因子的不同突变体为原型系统，给出了实验结果，并通过分子动力学模拟与理论研究结果进行了比较。

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THz-biology: studying protein dynamics in solution

THz spectrometer to measure absorption spectra of solvated proteins is developed. The radiation source is a p-type germanium laser which delivers output powers of several watts in the THz regime (from 1-4 THz). Experimental results for different mutants of ubiquitin and /spl lambda/-repressor which serve as prototype systems is presented and compared with theoretical studies using molecular dynamics simulation.

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Infrared and Millimeter Waves, Conference Digest of the 2004 Joint 29th International Conference on 2004 and 12th International Conference on Terahertz Electronics, 2004.

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