印尼北苏门答腊岛多巴和默拉皮山国家公园10种提取物的抗菌活性研究

IF 0.5 3区 数学 Q3 LOGIC
M. Ismayati, D. Zulfiana, S. Himmi, D. Tarmadi, D. Meisyara, A. Zulfitri, T. Kartika
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引用次数: 0

摘要

研究植物提取物的有益化合物是防止生物多样性丧失的途径之一。本研究通过计算微生物生长抑制区,评价了产自多巴、北苏门答腊和默拉皮山国家公园地区的本土植物提取物对大肠杆菌、枯草芽孢杆菌、i型鲑鱼、金黄色葡萄球菌、白色念珠菌和热带念珠菌的抑菌活性。其中香椿提取物t5对白色念珠菌、枯草芽孢杆菌、伤寒沙门氏菌和大肠杆菌的抑菌效果最好,其抑菌直径分别为2.00、1.80、1.33和1.33 cm。基于这些结果,随后分别用正己烷、乙酸乙酯和甲醇对中华赤霉素进行分馏。并对所得组分进行了抗菌生物测定。所有馏分在1%浓度下均表现出抑制微生物生长的活性。然而,每个部分对某些微生物的生长都有抑制作用。正己烷部分对大肠杆菌和伤寒沙门氏菌的抑制活性最大;枯草芽孢杆菌和白色念珠菌的乙酸乙酯部分;甲醇馏分用于大肠杆菌和伤寒沙门氏菌。结果表明,三叶草植物提取物具有很大的抗菌潜力。黄芪粗提物的抑菌作用模式有待进一步研究。制成。印尼生物多样性的开发潜力为植物资源的经济开发和保护开辟了一条新的途径。关键词:抗菌植物,本土知识,多巴-北苏门答腊,默拉皮山
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antimicrobial Activity of Ten Extractives from Toba, North Sumatra and Mt. Merapi National Park Regions, Indonesia
Investigating beneficial chemical compounds of plant extracts is one of the ways to prevent biodiversity loss. This study evaluated the antimicrobial activity of indigenous plant extracts from Toba , North Sumatra, and Mt. Merapi National Park regions against Escherichia coli , Bacillus subtilis , Salmone l la typ h i , Staphylococcus aureus , Candida albicans , and Candida tropicalis by calculating the zone of microbial growth inhibition. Among the plant extracts, T 5 that identified as Toona sinensis showed the highest microbial inhibit ion to the growth of C. albicans , B. subtilis , S. typhi, and E. coli with the diameter growth of approximately 2.00, 1.80, 1.33, and 1.33 cm, respectively. Based on those results, T. sinensis was then subsequently fractionated using n-hexane, ethyl acetate, and methanol , respectively. The resulted fractions also were evaluated for antimicrobial bioassay. A ll fractions have shown activity in inhibiting the growth of the microbes at 1% concentration. However, each fraction show ed growth inhibition against certain microbe s . The n-hexane fraction show ed the greatest inhibitory activity for E. coli and S. typhi ; ethyl acetate fraction for B. subtilis and C. albicans ; and methanol fraction for E. coli and S. typhi . The results revealed that T. sinensis plant extract has great potential as an antimicrobial agent . Further investigation is needed to observe the mode of anti microbial action of fractionated crude extracts of T . Sinensis . The exploring potency of Indonesian biodiversity opened up a new way for the utilization of plants for economic development and conservation . Keywords:  antimicrobial plants, indigenous knowledge, Toba-North Sumatra, Mt. Merapi
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来源期刊
CiteScore
1.20
自引率
16.70%
发文量
79
审稿时长
6-12 weeks
期刊介绍: The Journal of Symbolic Logic publishes research in mathematical logic and its applications of the highest quality. Papers are expected to exhibit innovation and not merely be minor variations on established work. They should also be of interest to a broad audience. JSL has been, since its establishment in 1936, the leading journal in the world devoted to mathematical logic. Its prestige derives from its longevity and from the standard of submissions -- which, combined with the standards of reviewing, all contribute to the fact that it receives more citations than any other journal in logic.
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