Mucinous Carcinoma of Gall Bladder an Incidental Finding of a Rare Case

IntroductionGall bladder carcinoma is the most frequent carcinoma of the biliary tract. Pure mucinous adenocarcinoma as seen in breast, skin, and pancreas are very uncommon in the gall bladder. Mucinous adenocarcinoma of gall bladder is rarer variant of gall bladder carcinoma. MethodsWe were reported a case of 55 years old male presenting at department of surgery of LLR and Associated Hospital with nonspecific symptoms of diffuse pain abdomen with nausea and vomiting, generalized weakness, itching all over body, jaundice associated with anorexia and weight loss for last 4 to 5 months, ultrasonography revealed gross thickening of wall of gall bladder neck with ill define mass lesion and diagnosis was confirmed by USG guided FNAC, Histopathological examination and Immunohistochemistry (IHC). RESULTSPatient present with pain abdomen, icterus and anorexia, on USG guided FNAC cytological and Histopathological findings are suggestive of mucinous adenocarcinoma. ConclusionMucinous adenocarcinoma is the rarest variant of adenocarcinoma gallbladder. Incidental diagnosis of mucinous adenocarcinoma of gall bladder was found by USG guided FNAC followed by the histopathological examination. Key-wordsMucinous Adenocarcinoma, Gall bladder, FNAC, Mucin INTRODUCTION Gall bladder carcinoma is the sixth most common malignant tumor of gastrointestinal tract and most frequent carcinoma of biliary tract. Approximately 3:1 ratio between female: male occur. Most patients are older than 50 years [1] . About 99% of gall bladder cancer are carcinoma including more than 90% of them were adenocarcinoma. Carcinomas with copious mucin production are now thought to form distinct category among malignancies of gall bladder. [2-3] Mucinous carcinoma constitute 2.5% of gall bladder carcinoma other sub type include papillary adenocarcinomasquamous cell and adenosquamous carcinoma. Gall bladder carcinoma more common in females than males and its incidence increases with age [4] . Cases in which stromal mucin deposition constituted more than 50% of tumor were classified as mucinous carcinoma according to current WHO Classification. [5,10] Cases in which the mucin was confined to the lumina of the infiltrating glandular units, but not present in to the stroma, were not Access this article online Quick Response Code Website: