雪松精油对应激大鼠血清皮质醇水平的影响

Jose Giovanny
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摘要

当前位置压力是身体对任何可能影响身体内分泌系统的需求的一种反应,比如皮质醇释放到血液中。精油被广泛用于压力治疗,因为它们有镇静作用。其中之一是雪松精油。本研究旨在研究雪松香膏对应激大鼠血清皮质醇水平的影响。本研究随机选取雄性大鼠wistar。这只动物被暴露在强迫游泳测试中作为应激源,然后他们被给予雪松香膏。我们使用了3组,第一组每天进行强迫游泳测试,并在剃光的背部涂上雪松香膏,第二组每天只进行强迫游泳测试,第三组什么都不给。30 d后采用ELISA法测定血清皮质醇水平。各组采用Kruskal Wallis检验,后验采用man whitney检验(p < 0.05)。雪松香膏组血清皮质醇水平显著低于其他各组。两组比较,血清皮质醇水平差异有统计学意义(p = 0.018)。综上所述,雪松香通过内分泌调节机制调节应激反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Essential Oil of Cedarwood (Cedrus Atlantica) against Serum Cortisol Levels in Rats Which Were Given Stressor
: Stress is a response of the body to any demand that can affect the body’s endocrine system such as the release of cortisol into the bloodstream. Essential oils have been widely used for stress treatment because they have a calming effect. One of them is cedarwood essential oil. This study was conducted to determine the effect of cedarwood balm against serum cortisol levels in rats which were given stressor. In this study wistar male rats were randomly selected. This animal was exposed to forced swim test as stressor and then they were given cedarwood balm. We used 3 groups, the first group were given a daily forced swim test and applied cedarwood balm on the shaved back, the second group were given a daily forced swim test only, the third group were given nothing. Their serum cortisol levels were measured by ELISA test after 30 days. Result were analysed by Kruskal Wallis test for all group and man whitney test as a post test (p < 0,05). Serum cortisol level was significantly lower in cedarwood balm group then the other groups. When the all group were compared, serum cortisol level was significantly different (p = 0,018). In conclusion this indicates that cedarwood balm affect the endocrine regulatory mechanism to modulate stress responses.
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