家族性特发性肺纤维化发生在一个家庭的四名成员中

Respiratory Medicine Extra Pub Date : 2007-01-01 DOI:10.1016/j.rmedx.2007.01.003

AnneMarie Mc Laughlin, Rosemary O’Brien, Seamas C. Donnelly

{"title":"家族性特发性肺纤维化发生在一个家庭的四名成员中","authors":"AnneMarie Mc Laughlin, Rosemary O’Brien, Seamas C. Donnelly","doi":"10.1016/j.rmedx.2007.01.003","DOIUrl":null,"url":null,"abstract":"<div><p>Idiopathic pulmonary fibrosis<span> (IPF) is a progressive fatal lung disease characterised by persistent pulmonary inflammation. Approximately 2% of cases are familial. Herein, we describe a family in which four members over two generations developed IPF. Of particular interest, the age of onset was lower in the second generation affected by the disease. Familial IPF offers a unique opportunity to study the proinflammatory processes implicated in IPF.</span></p></div>","PeriodicalId":101082,"journal":{"name":"Respiratory Medicine Extra","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedx.2007.01.003","citationCount":"0","resultStr":"{\"title\":\"Familial idiopathic pulmonary fibrosis occurring in four members of a family\",\"authors\":\"AnneMarie Mc Laughlin, Rosemary O’Brien, Seamas C. Donnelly\",\"doi\":\"10.1016/j.rmedx.2007.01.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Idiopathic pulmonary fibrosis<span> (IPF) is a progressive fatal lung disease characterised by persistent pulmonary inflammation. Approximately 2% of cases are familial. Herein, we describe a family in which four members over two generations developed IPF. Of particular interest, the age of onset was lower in the second generation affected by the disease. Familial IPF offers a unique opportunity to study the proinflammatory processes implicated in IPF.</span></p></div>\",\"PeriodicalId\":101082,\"journal\":{\"name\":\"Respiratory Medicine Extra\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2007-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.rmedx.2007.01.003\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Respiratory Medicine Extra\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1744904907000021\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Respiratory Medicine Extra","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1744904907000021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

特发性肺纤维化(IPF)是一种以持续肺部炎症为特征的进行性致死性肺病。大约2%的病例是家族性的。在这里，我们描述了一个家庭，其中四名成员超过两代发展IPF。特别有趣的是，患病第二代的发病年龄较低。家族性IPF为研究IPF中涉及的促炎过程提供了一个独特的机会。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Familial idiopathic pulmonary fibrosis occurring in four members of a family

Idiopathic pulmonary fibrosis (IPF) is a progressive fatal lung disease characterised by persistent pulmonary inflammation. Approximately 2% of cases are familial. Herein, we describe a family in which four members over two generations developed IPF. Of particular interest, the age of onset was lower in the second generation affected by the disease. Familial IPF offers a unique opportunity to study the proinflammatory processes implicated in IPF.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Respiratory Medicine Extra

自引率

0.00%

发文量