A. Dogara, A. A. Lema, H. Hama, S. Hamad, Nor Hasima Mahmod Mohammad, Mohammad Moneruzzaman Khandaker, Wandayi Emmanuel Amlabu
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引用次数: 0
摘要
刺虫科有18属540种。Boswellia dalzielii是热带和亚热带地区用于治疗和管理各种疾病的药用植物。尽管dalzielii具有药用价值,但没有全面的文献记载。本文综述了黄刺莲的民族药理学、生物学评价及化学成分。检索了Scopus、Web of Science、BioMed Central、Science Direct、PubMed、Springer Link和Google Scholar来查找已发表的文章。结果表明,在尼日利亚、喀麦隆、布基纳法索、贝宁、苏丹和几内亚,达尔齐莱叶、茎皮和根传统上用于治疗和管理抗风湿、抗痉挛、镇痛、防腐、降压、疟疾性精神疾病、溃疡、疼痛和发烧。叶、茎、皮、根均具有抗氧化、抗菌、抗真菌、抗疟等作用,其中以茎叶活性最高。化学成分分析表明,黄芪叶中单萜化合物含量较高,主要成分为α -蒎烯。根据文献调查,该物种主要是在体外研究的。需要精心设计的临床实验来获得结论性证据。应建立登机的标准剂量和安全性。
Ethnopharmacology, Biological evaluation and Chemical composition of Boswellia dalzielii Hutch: A Review
The Burseraceae family consists of 18 genera and 540 species. Boswellia dalzielii is a medicinal plant used in tropical and subtropical areas for the treatment and management of various ailments. Despite the medicinal value of B. dalzielii, there is no comprehensive documentation. The study aimed to review the ethnopharmacology, biological evaluation and chemical composition of B. dalzielii. Scopus, Web of Science, BioMed Central, Science Direct, PubMed, Springer Link, and Google Scholar were searched to find published articles. The results showed that the leaves, stem bark, and root of B. dalzielii have been traditionally used in Nigeria, Cameroon, Burkina Faso, Benin, Sudan, and Guinee for the treatment and management of antirheumatic, antispasmodic, analgesic, antiseptic, hypotensive, malarial mental illness, ulcer, pain, and fever. It is also found that leaves, stem bark, and root have antioxidant, antibacterial, antifungal, and antimalarial properties with stembark having the highest activity. Chemically, it was revealed the leaf has high contents of monoterpenes hydrocarbons with alpha-pinene as the major compound. The species were largely studied in vitro, according to the literature survey. A well-designed clinical experiment is required to obtain conclusive evidence on the efficacy of stembark. The standard dose and safety of the stembark should be established.
期刊介绍:
The journal had been established in 1972, and online publication was begun in 2008. Since 2012, the journal has been published in English by Faculty of Pharmacy Universitas Gadjah Mada (UGM) Yogyakarta Indonesia in collaboration with IAI (Ikatan Apoteker Indonesia or Indonesian Pharmacist Association) and only receives manuscripts in English. Indonesian Journal of Pharmacy is Accredited by Directorate General of Higher Education. The journal includes various fields of pharmaceuticals sciences such as: -Pharmacology and Toxicology -Pharmacokinetics -Community and Clinical Pharmacy -Pharmaceutical Chemistry -Pharmaceutical Biology -Pharmaceutics -Pharmaceutical Technology -Biopharmaceutics -Pharmaceutical Microbiology and Biotechnology -Alternative medicines.