在尼日利亚拉各斯获得肾脏移植的挑战

C. Amira, A. Busari, B. Bello
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摘要

背景:肾移植(KT)是治疗终末期肾病(ESRD)的最佳形式;然而,在世界范围内,在移植的道路上存在潜在的障碍。目的:本研究的目的是确定尼日利亚拉各斯KT计划的主要障碍。材料和方法:本研究是一项横断面描述性研究,研究对象为2012年1月至2014年12月在拉各斯大学教学医院接受常规透析治疗至少3个月的ESRD患者。使用预测问卷,获得相关的临床和人口统计信息,包括获得肾移植计划所面临的挑战。结果:共纳入患者57例,其中男性30例(52.6%),平均年龄40.6±12.8岁。ESRD的常见病因为高血压(40.4%)和慢性肾小球肾炎(26.3%)。平均透析时间为8.7±5.84个月(3 ~ 28个月)。最大的挑战是缺乏供体和缺乏资金(38.5%),而25%的人说他们有供体但缺乏资金,5.8%的人有资金但没有供体,7.7%的人说他们在研究时没有为肾脏移植做好心理准备。结论:尼日利亚KT面临的最大挑战是捐助方和资金短缺。政府和健康保险机构应将肾脏替代疗法纳入其政策。可以通过在尼日利亚设立已故捐助者移植方案来扩大捐助者库。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Challenges accessing kidney transplantation in Lagos,Nigeria
Background: Kidney transplantation (KT) is the best form of treatment for end-stage renal disease (ESRD); however, worldwide, there are potential barriers along the pathway to transplantation. Objective: The aim of this study was to identify the major impediments to KT programme in Lagos, Nigeria. Materials and Methods: This was a cross-sectional, descriptive study of patients with ESRD who have been on regular dialysis for at least 3 months at the Lagos University Teaching Hospital from January 2012 to December 2014. Using pretested questionnaire, relevant clinical and demographic information was obtained including the challenges faced with access to kidney transplant programme. Results: Fifty-seven patients were recruited, of which 30 (52.6%) were male, with a mean age of 40.6 ± 12.8 years. The common aetiologies of ESRD were hypertension (40.4%) and chronic glomerulonephritis (26.3%). The mean duration on dialysis was 8.7 ± 5.84 months (range, 3–28 months). The greatest challenges were lack of donors and lack of funds in 38.5% concurrently, whereas 25% said that they had donors but lack the funds, 5.8% had funds but no donor and 7.7% said that they were not psychologically prepared for kidney transplant at the time of the study. Conclusion: The greatest challenge to KT in Nigeria was scarcity of both donors and funds. Government and health insurance agencies should incorporate renal replacement therapy into their policies. The donor pool could be expanded through establishment of deceased-donor transplant programme in Nigeria.
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