大网膜瓣早期治疗胸骨深部伤口感染

Ashraf Zahra , Hosam F. Sayed , Mohamed Abd El-Hafez Fouly , Mahmoud Ghalwash
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引用次数: 1

摘要

背景:胸骨深部伤口感染(DSWI)是一种严重的并发症,发生率为0.3%-5%的胸骨切开术后患者。与此同时,对于心脏直视手术后胸骨伤口感染的最合适的外科治疗方法尚无共识。在这项回顾性研究中,我们旨在评估早期和晚期使用网膜皮瓣治疗DSWI和纵隔炎。方法本回顾性研究纳入了具有不同危险因素、感染程度和治疗时机的心脏直视手术后DSWI患者。网膜瓣取自大网膜,经横膈膜切口转置于胸膜腔内。结果15例患者中,糖尿病患者7例(46.6%),慢性阻塞性肺疾病患者8例(53.3%)。由于内毒素血症引起的革兰氏阴性感染以及耐甲氧西林金黄色葡萄球菌等耐药感染可发生严重的纵隔炎。11例患者在清创后进行了初级网膜瓣覆盖(I组),而另外4例患者进行了胸骨重新连接,随后进行了网膜瓣覆盖(II组)。I组中只有3例患者(27.2%)术后死亡,而II组中有4例患者(100%)术后死亡。在I组患者中,8例早期网膜瓣覆盖(IA), 3例晚期网膜瓣覆盖(IB)。只有2例患者在早期治疗后死亡,而7例患者中有5例(71.4%)(IB组和II组)死亡。结论早期应用网膜皮瓣治疗纵隔炎的预后优于重线治疗。这应包括高度的临床怀疑和术后对临床表现的密切随访。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Early management of deep sternal wound infections using omental flaps

Background

Deep sternal wound infections (DSWI) are a grave complication that occurs in 0.3%–5% of post-sternotomy patients. In the meantime, there is no consensus over the most appropriate surgical management for sternal wound infections, following open heart surgery. In this retrospective study, we aimed to evaluate the early versus late use of omental-flaps for DSWI and mediastinitis.

Methods

This retrospective study included patients with DSWI following open cardiac surgeries with variable risk factors, degrees of infection and timing of management. The omental-flap was obtained from the greater omentum and transposed into the pleural cavity through a diaphragmatic incision.

Results

Out of the 15 enrolled patients, seven (46.6%) were diabetics and eight (53.3%) had chronic obstructive pulmonary disease. The severe form of mediastinitis occurred with gram-negative infections due to endotoxemia, as well as with resistant infections as methicillin-resistant staph aureus. Eleven patients had a primary omental-flap coverage after debridement (group I), while the other four underwent sternal rewiring, followed by omental-flap coverage (group II). Only three patients (27.2%) in group I died post-operatively, compared to four patients (100%) in group II. Among group I patients, eight had an early omental-flap coverage (IA), while three had a late coverage (IB). Only two patients died after early management, while five out of the seven (71.4%) patients (groups IB and II) died.

Conclusions

Early management of mediastinitis through omental-flaps has a better prognosis than rewiring. This should include a high index of clinical suspicion and a close post-operative follow-up of clinical manifestations.

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