Type 2 Diabetes Mellitus

The incidence of diabetes mellitus (DM) is increasing particularly in the developing nation. It is also one of the major global public health problems. The World Health Organization (WHO) predicts that over 330 million people worldwide will have DM and around 5-10% of national health care budget are estimated to be allocated for DM alone by 2030 WHO [1]. DM also is closely related to the increase of premature and preventable death. The number of death attributed directly or indirectly to DM has reached 3.7 million in 2012 WHO [2]. The chronic hyperglycaemia (an abnormally high amount of glucose level in blood) of diabetes is associated with long-term damage, dysfunction, and failure of various organsand other macro and microvascular diseases, such as end-stage renal failure, blindness, heart disease, stroke, dementia and leg amputation Cade [3]; WHO [2].